Page 14 - iAV Digital Magazine #402

The only true FREE CLASSIFIEDS in the Antelope Valley... Where buyers and sellers meet!
TOOLS &
EqUIPMENT
Carpenter/Concrete tools, 100feet electrical cords & other items. Make offer •
943-6071 406
2)Ladders: Wooden $25 & Extension ladder $35 • 718- 2020402
Craftsman garage door opener, 3/4hp $150 • 728- 7687402
Powermate generator, 4000watt, needs TLC $150 • 728-7687402
Over 100pcs including locks & timing lights $59 • 435-
402 3926
4) 16ft extesion ladders
$60ea • 942-0820 401
2 Extension ladders, 28ft high, $120ea • 733-7007401
HOmE SERViCES
CuSToM kiTChen CounTerS Fabricator & Installer Payless for Granite, Marble, Quartz, Travertine, Limestone Granite $25/sqft includes fabrication & installations 818-738-4368 Locally owned & Operated
HOUSEWARE
Large oil hand painting, Spanish senorita. Signed by artist • 722-6785• 722-6785404
Very good crystal , large bowl & tall vase $35 for both • 722-6785404
2)Throw rug, xlnt cond, 5’x8’ $30 • 943-6071403
Large beautiful Belgian rug, light green & beige color. No burns or holes, very lovely $135 • 722-6785402
Free: X’mas decorations & other items • 943-6071402
Lots of household items. Too many to list. Pots, pans, dishes, plates, furnitures, tools & several items • 943- 6071406
Dinnerware set for 20peo- ple, make offer • 943-6071399
Magic Chef mixer w/ all accessories, heavy duty $150 • 943-6071399
Hersheys kisses canisters & dispenser. 1 canister from 1982 Made in England, 1 in 1995 American. Also plastic table top dispenser. Great for Hershey or old candy memorabilia collectors $50 for set. I will not break • 272-9273 bet 8:30am-
8:30pm only373
New Ceasar Chavez framed wall poster/ picture. 40”high x 30”wide x 1” thick. This would look great on your wall $29 • 272-9273 bet
8:30am-8:30pm only
373
APPLIANCES
2 window air conditioners. One is huge, work great $75each • 206-5815404
Blinkman smoker, Jack Daniel, new $150 • 236- 8293404
Heir mini fridge, silver $70 •
236-8293 404
Mini refrigerator, blck, Igloo $60 • 236-8293404
GE washer, white, xlnt cond $175 • 236-8293404
New ceiling fan light fixture in box. $25, Harbor Breeze • 272-9273 bet 8:00am- 8:30pm only404
New turkey fryer, large size w/ full tank of propane, xlnt
403 cond $60 • 943-6071
Chest freezer, white. Looks & works great $125 • 272- 9273 bet 8:00am-8:30pm only403
Neptune washer, good cond, large cap, like new $200 • 264-3870402
Kitchen Aid juicer $50; Lots of other kitchen elec- tronic items. Call for details
• 943-6071
402
Large upright freezer, works perfectly $100 • 943-6071401
Whirlpool Electric Dryer, Apt Size, works. $60 • 533- 5533401
Made in America, Coil Burners, about 30 months old, everything works. $150 • 533-5533401
Electric dryer, white, large capacity $80 • 264-3870402
KIDS STUFF
& TOYS
Children bedroom set. Dresser, chairs w/ antique rack over the dresser $100 • 943-6071406
Rocking hammock for new- born $30; Baby walker $40; Mirror $40 • 718- 2020404
Baby organizer $10 • 718- 2020402
Baby cradle, vibrates $25 • 718-2020402
Baby center $45 • 718- 2020402
Baby crib, complete, like new $20 • 947-4343399
First, There Were Wearables. Now, There Are Swallowables
Zack Guzman In the evolution of computing, from the desktop com- puter to the smart- phone to the watch, it seemed like just a matter of time before the technology would come to be swal- lowable — and now it is.
The innovation at the heart of it is an FDA-approved ingestible sensor housed in pills, designed to help patients adhere to the medications their doctors prescribe. Except the sensor isn't powered by a battery, it's powered by the gut of the patient swallowing it, using technology discov- ered two centuries ago.
"We have a small, food- particle-sized piece of silicon, an integrated cir- cuit, and on one side of that circuit is a film of copper, on the other side a very thin film of mag- nesium," explained Proteus Digital Health co-founder Dr. George Savage. "When you swallow, these minerals get wet and two dissimi- lar metals in aqueous contact define a battery, so you become a bat- tery." From there, the powered pill sensor sends a signal to a patch worn on the body, which sends data via Bluetooth to a phone or tablet and on to the cloud for a doctor or caregiver.
The patient-as-a-battery idea sounds simple enough, and the compa- ny likens the process to a child's science-fair experiment, but this one garnered more than 350 patents and received more than $400 million in funding from some of the biggest names in health care, including Novartis, Medtronic,
Kaiser Permanente at a unicorn valuation.
"What's the most com- mon thing that some- body who is sick is sup- posed to do every day? Swallow their medicine," Proteus CEO Andrew Thompson told CNBC.
The only problem is, they don't.
According to the World Health Organization, about half of all patients with chronic illnesses, such as cardiovascular disease or high blood pressure, fail to take their medications as pre- scribed. By some esti- mates, such nonadher- ence in the U.S. can add up to 10 percent of hos- pitalizations in older adults, costing the health-care system $100 billion to $300 billion.
"If you give people, for example, five medica- tions to take a day and you say take this in the morning, take this at lunch time, take this in the evening, that's very complicated," Thompson said. "So what we're showing is the beginning of a solution ... to one of the single biggest prob- lems in all of health care, which is to help you take your medicines appropri- ately."
In the latest of Proteus' 67 clinical trials, prelimi- nary results demonstrat- ed that patients suffering from uncontrolled high blood pressure who were prescribed the digi- tal pill had "dramatically lower blood pressure ... with about 85 percent of patients at four weeks in the Proteus groups achieving their goal, ver- sus about 33 percent in the usual care group," Savage said.
Noting the differences between tech and health care, Thompson said the company isn't looking to expand its services too quickly, only starting its first use outside of a clin- ical setting this January with hundreds of patients and their doctors at South Lake Tahoe, California–based health system Barton Health, before looking into licensing the technology to big pharma compa- nies.
While the implications have many in the med- ical field excited at pos- sibilities, questions sur- rounding the technology have shifted from "will this work?" to "how will this be used?"
"If I'm taking pills to con- trol my hypertension,
that's one thing, but if I'm taking pills to control my drug addiction, who gets to see that and who knows about it is a very different thing," New York University bioethi- cist Arthur Caplan told CNBC. "I think there are vulnera- ble groups out there for whom this technology might not be seen as the world's biggest gift."
Thompson said
the company had initially explored alterna-
tive use cases such as monitoring antibiotic adherence in tuberculo- sis patients to prevent the rise of antibiotic resistance, or parents working to help children with mental-health issues, but wanted to make clear Proteus' mis- sion is "the empower- ment and the enable- ment of our patients to get well."
The FDA recently reject- ed Proteus' first attempt to place its digital sensor directly into its first med- ication, Abilify, a drug commonly prescribed for schizophrenics. The agency requested more data and testing to eval- uate use-related risks.
Yet as cutting edge as the idea of swallowing a computer seems, at the heart of the issue is a problem as old as the Hippocratic Oath. As the ancient Greek physician Hippocrates notes in On Decorum, "Keep a watch ... on the faults of the patients, which often make them lie about the taking of things pre- scribed. For through not taking disagreeable drinks, purgative or other, they sometimes die."
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