Page 9 - Gates-AnnualReport-2018

The Gates Center currently focuses research resources and recruiting efforts in the following areas of expertise:
Platform Technologies applied across multiple areas of medicine (see discussion of the Stem Cell Biobank and Disease Modeling Core on page 36)
Applied Technology and Translational Programs in:
• Cardiology
• Dermatology
• Neurology
• Oncology
• Ophthalmology
• Orthopedics
• Pulmonary science
• Wound healing
Dennis Roop, Ph.D., recruited from the Baylor College of Medicine in 2007, is the Center Director and coordinates a
talented array of 114 multi-institutional researchers from the Anschutz Medical Campus, CU Boulder, CU Denver, Colorado State University, Colorado School of Mines and National Jewish Health, as well as private industry. The Gates Advisory Board, comprised of community leaders and clinicians, provides counsel and additional support (see page 7).
Key to the success of the Gates Center is the partnership with the Gates Biomanufacturing Facility, a state-of-the- art manufacturing facility translating innovative research discoveries into safe and effective cell therapy and protein biologic products for human clinical trials. The GBF contains 7,000 square feet of “clean room” operated under FDA “Good Manufacturing Practice” guidelines, which assure proper design, monitoring and control of manufacturing processes and facilities. The GBF has proven essential in engagement of research talent present on the Anschutz Medical Campus as well as in talent recruitment nationwide.
Regenerative medicine includes research into the uses of adult stem cells, which can be reprogrammed into embryonic-like stem cells and then differentiated into virtually any cell type in the body. These core tools are referred to as induced Pluripotent Stem Cells (iPSCs). The long-term goal is to return iPSC-derived adult stem cells to the patient from whom they were derived in order to regenerate cells, organs and key bodily functions. Other research includes production and manipulation of key proteins in the body to fight or correct disease; and the alteration of a patient’s own T cells to produce CAR-T cells for immunotherapy to combat cancer.
David Norris, M.D., Professor and Chairman, Department of Dermatology, has been a perennial champion and collaborator of the Gates Center.
Retiring Gates Center Advisory Board member Dori Biester with Allison Krebs
Gates Summer Internship Program students listened to guest speaker
Gates Center for Regenerative Medicine 9 during final day ceremonies held on August 10, 2018.