Page 24 - Establishing the Institute for Brain and Neural Sciences

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Unlike the expansive growth and adaptation of neurons in early development, central nervous system neurons undergo little or no regeneration following injuries later in life, such as those to the spinal cord. This failure of resilience has been attributed to a combination of external factors such as scar tissue and internal factors like a loss of the ability to grow.
8 CENTER FOR RESEARCH ON INJURY AND REGENERATION
Why is the nervous system W
slow to recover? How can we harness our knowledge of neurodevelopment to repair damage to the brain and spinal cord?
eizmann Institute scientists are
from neighboring tissue. Researchers will also draw insights from organisms such as sh and amphibians, who regenerate neurons with far greater e ciency than mammals do. These insights are expected to lead to therapies and tools to rewire and regenerate injured neurons and return individuals to full health after injury such as stroke or accidents.
using a variety of methods to better understand neurodevelopment in order to shed light on how to impel damaged neurons to regenerate. Research in this center will address such fundamental matters as the response to injury and the growth potential of damaged neural tissue— which is due not only to the neuron itself, but also to the support it receives