Page 20 - Randlab Catalogue New Zealand Edition

Antibiotic
enroTM 100 INJeCtABLe sOLUtION
ACVM Act 1997 No.A11232
Anti-infective agent for the therapy of specific diseases caused by susceptible bacteria
Spectrum of activity: Randlab Enrofloxacin 100 Injectable Solution is active against a wide range of gram negative and gram positive bacteria and Mycoplasma species.
Randlab Enrofloxacin 100 Injectable Solution is reserved for use for the following indications only:
1. Bacterial infections of bones in pigs and cattle.
2. Mastitis in cows where the causative organisms have been established to be either E. coli or Pseudomonas. Appropriate intramammary treatment with another antibiotic should be used in combination with systemic treatment (other than oral) with Randlab Enrofloxacin 100 Injectable Solution.
3. Infection of the male reproductive tract (prostatitis, vesiculitis, orchitis) in the bull.
4. Certain infections of cattle and pigs, in locations where poor tissue penetration by other antimicrobial drugs can be expected and where the condition is caused by a susceptible organism which is not expected to respond readily to other antibiotics.
Directions For Use
DOSAgE AND ADMINISTRATION
Cattle & Pigs: Basic Dose Rate: 2.5 mL per 100 kg bodyweight per day for 3 days.
Severe respiratory Infections: 5.0 mL per 100 kg bodyweight per day for 3 days.
Meat Withholding Period: MEAT: Animals producing meat or offal for human consumption must not be sold for slaughter either during treatment or within 7 days of the last treatment.
MILK: Milk intended for sale for human consumption must be discarded during treatment and for 168 hours (7 days) following the last treatment.
It is an offence for users of this product to cause residues exceeding the relevant MRL in the New Zealand (Maximum Residue Limits of Agricultural Compounds) Food Standards.
Racing/Event Withholding Period: If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.
First Aid: If poisoning occurs, contact a doctor or Poisons Information Centre. Phone Australia 131126 or in New Zealand 0800 764 766.
Disposal: Dispose of empty container by wrapping with paper and putting in garbage. Discarded needles/ sharps should immediately be placed in a designated and appropriately labelled “sharps” container.
Storage: below 25°C (Air conditioning). Protect from light. Following withdrawal of the first dose, use the remainder of the vial within 28 days or discard the unused portion. Dispose of empty container by wrapping with paper and putting in garbage.
ACTIVE CONSTITUENT
ACTIVE CONSTITUENT
100 mg/mL ENROFLOXACIN
Enrofloxacin 100 mg/mL
PACK SIZE
PACK SIZE
100mL Single Vial
100mL single vial
For subcutaneous injection in cattle and intramuscular injection in pigs.
Indications
Bacterial infections of bones in pigs and cattle. Mastitis in cows where the causative organisms have been established to be either E. coli or Pseudomonas. Appropriate intramammary treatment with another antibiotic should be used in combination with systemic treatment (other than oral) with Enrofloxacin 100. Infection of the male reproductive tract (prostatitis, vesiculitis, orchitis) in the bull. Other infections of cattle and pigs where poor tissue penetration by other antimicrobial drugs can be expected and where the condition is caused by a susceptible organism which is not expected to respond readily to other antibiotics. Indiscriminant use of antibiotics may lead to the development of resistance. Randlab Enrofloxacin 100 should be used in individual animals in line with the above recommendations. Treatment of groups of food producing animals is only recommended when culture and sensitivity testing indicate Randlab Enrofloxacin 100 is the only product likely to be effective.
CHEMISTRy: Randlab Enrofloxacin 100 Injectable Solution contains enrofloxacin, an anti-bacterial of the 4-quinolone group.
MODE OF ACTION: Randlab Enrofloxacin 100 Injectable Solution inhibits the enzyme DNA gyrase which plays a major role in the replication of DNA. Inhibition of this enzyme leads to functional disturbances with blockage of certain stages in synthesis, resulting in death of the bacterium. This mode of action rules out cross resistance between Randlab Enrofloxacin 100 Injectable Solution and other anti-bacterials commonly used in veterinary medicine.
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