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EDUCATIONAL RESOURCES
Randlab’s Educational Resources
Keep up to date with the latest research and advancements
Educate, Train, Instruct and Inspire.
Tech Talk
The Tech Talk was designed by Randlab to keep equine veterinarians abreast of the latest research and developments on selected topics in equine veterinary medicine and surgery.
The newsletter is managed by Randlab with our Global Technical Veterinary Director, Dr Michael Robinson, acting as the editor. We also have contributing guest authors who are experts in their field. This allows Randlab to keep the topics relevant and balanced in their discussion.
You can download all of the Tech Talk’s from the Randlab website under the resource section – just go to randlab.com/ resources.html.
Trainer’s Tips and Stable Talk
Trainer’s Tips and Stable Talk are designed to bring the latest scientific research on a specific topic to the end user (horse owners and trainers). These are released in parallel with the Trainer’s Tips and provide a simplified user-friendly version of the information contained in the Trainer’s Tips. They are a great resource for veterinarians to hand out to their clients when discussing specific clinical cases.
Quarterly Newsletter
The Randlab Quarterly Newsletter features a lead article that highlights discussions and controversies surrounding a current “hot topic”. The Newsletter also contains news snippets covering recent scientific articles, past and upcoming equine veterinary educational events and general items of interest.
Randlab is committed to the continuing professional development of the Equine Veterinarian Community

RANDLAB
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VETERINARY MEDICINES
Issue 1
WWW.RANDLAB.COMA.ACUTIVETCHOE NSEWTISTLEUTETENRTF:OMR WELINONXINCGAMTRA2IN0EmRSg/mL SPRING 2018 Offering trainers, owners and horsemen science-based practical solutions to common problems. For alleviation of inflammation
        
The condition is significant enough to
have its own Advisory Council which recently published a Consensus Statement to provide veterinarians with guidelines regarding the pathophysiology, diagnosis and treatment of EGUS1. The foundation of the Consensus Statement is evidence- based medicine and, where not available, interpretive recommendations.
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EGUS is best regarded as two separate entities; EquineSquamousGastricDisease(ESGD)and Equine Glandular Gastric Disease (EGGD) . The two conditions may occur either independently or concurrentlyinthesamehorse.Thepresenceor absence of one cannot be used as a predictor for the presence of absence of the other .
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horses.
2. HowREaInPdHlaisbd.iagnosed: the relative merits of scoping vs lung wash EenIPdHosiscoupsyua(sllcyodpiea)gonfotsheedabiryweaityhseor r a lung wash (BAL).
ESGD is very common (between 11-95% depending on discipline and management) The causes of ESGD are well documented and it is known to be highly responsive to routine treatment with proton-pump inhibitors, such as omeprazole . EGGD is becoming more widely recognised (between 16-65% depending on discipline and management) as more veternarians seek out
the pyloric region of the stomach on routine gastrocopies. Visualisation of this region may be technically challenging but is an essential part of
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REFERENCES:
T2a0r0g8o;w17n9ik(4L):E3,19L-ix26L.M, Metge CJ, Prior HJ, Leung S and Leslie WD. Use of proton pump inhibitors and risk of osteoporosis related fractures. CMAJ 2008;179(4):319-26.
Schubert ML. Adverse effects of proton pump inhibitors: fact or fake news? Curr Opin Gastroenterol. 2018; 34(6):451-457.
TJaGrgaoswtrnoieknLteEr,oGl. o2e0r1t7zeJnaAnA;L1,1L2u(1o):Y9,5L-1e0sl1lie. WD. Long-Term Proton Pump Inhibitor Use Is Not Associated With Changes in Bone Strength and Structure. Am
J Gastroenterol. 2017 Jan;112(1):95-101.
CofaEstqouninSeSV,eFtrerdineariricykSscDieCn,cKee2rs0h15K;D3,5W, 7a1n4g-7C2.3S.hort-term omeprazole use does not affect serum calcium concentrations and bone density in horses. Journal of Equine Veterinary Science 2015; 35, 714-723.
NScieielsnecneB2D01, 7E;c5k7e,rt2S2M63,–R2o2b6i9s.on CI, Mills J, Peters D, Pease A, Schott II H. Omeprazole and its impact on mineral absorption in horses. Animal Production Science 2017; 57, 2263–2269.
HVeutnetriningatroiannPsJA,uPsatrgaalinan BJDai,nPFeatlrlosnkLi eLcAtu, rMesa,nSnyAdCnCe.yO. meprazole reduces calcium digestibility inSThUoroMughMbreEd HRors2e2es0. 210198. PNPNosEterWpreSsenLtaEtionTETquEineR
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The condition of Equine
Gastric Ulcer Syndrome
(EGUS) is well known
amongstequineveterinarians. RTahnisdldldatibcsobcoserimsuptnlrletaistmeOdeNntoLtYaonffAdeVrfAoitIsllLocAwliBeunLptEsreatatoq2ut0hir%edFd.IiRscSoTunTtHoffREtEthEenPoErmOaPlLrEegtiostrationfees!
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tinatkreodaucpinraggtmhiastinceawprpurloea.cIhtistoliktheelyAthltaretnaotgleassttisosumeeaonfdthgeootithearloSnteatebsy will introduce a similar threshold rule in the next few months. The V’landys interview is well worth listening to and can be downloaded here:https:// www.racingnsw.com.au/news/latest-racing-news/racing-nsw-ceo-peter- vlandys-discusses-regumate-and-altrenogest/
in Fal
ctures lon Le
SUMMARY TABLE: Omeprazole and Ca2+ / Bone density studies:
AVAILABLE NOW
management of gastric ulcers in your clients’ horses. Dr Michael Robinson on 0451 481 050 or mrobinson@randlab.com.au. Induced Pulmonary Haemorrhage (EIPH). Severe EIPH can result in epistaxis. Epistaxis is
DBSrc,EBlVliMeSC, rPihsDpe
Perth mare Enticing Star was publicly declared by owner Bob Peters to be in season the day before she raced in a recent Stakes race. The pfinreisvhioinugslyunupnlabceeadteannmdathresduefffearetdwhaesrbfilarsmteddefoenathienrebigehintgstianrtseawshoenn, wneitvhehrewrarindterddteoclbaerining theat,ra“Sceh”e.’sThinesmeasroeni,mlapirdoavelldovaetrhtheer nbeaxrrtiesrtsaratntod the run the race of her life to be narrowly beaten in a better quality Group 1 stakes race.
u check out the Randlab library at www.randlab.com.au/library.hEtmql. Aucciensseto tVheelibtraeryrisinfreae ry Education Disco
t
For access to a comprehensive library of journal articles on gastric ulcers and other topics, the presence of blood in one or both noEstrails.eIn of dosing ensuring
and there are hundreds of key scientific publications available fEor qreauding eon sVelected rtoipnicas. ry Education Discount
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2. The lack of coughing after a race does not mean that the sUtlrtoimngatenlyouthgihs btoarwriiethr sistanediththeer pthriecskseunreouingchretaosperseavsesnotcEiaIPteHd, nwoitrhtheixneercnioseu.gh
TrehgisitstdeiAsrcsaowtueneatllhchiassOcocotNheuLrYwesesAeAlVul-AsiAisknInLogAwtBhnLeLesEipspsgtnoescicithoaeflfRFRFaiIalRunrSdeTlTlatobTtHdhiRrocsocivEeE,unPtEcocoOdPeL.E to rFeogr ifsurttehwierernraedtpiegtepahaiaielt/s/sctlpehornoscgcsorea,aumparsonneneodtrhuhumecsococoinldaugtrcesestqho,uelseseiacslei,ptptyhge,ecacbfisoaeltllohoriwRacivnauginolwcduelrabrasisbltechd:haisavcneogutehnset,code.
https:s //wpwwo.teventptdi.a.ococl mto/cochuarseseves/s coca usrisesegn-s-silfiistsc/aunststriamliap-naecwt-ezeoanlatnhd-eanhdo-arsisae#’asutsts ralia
To obtcaointyaocut ryoduisrclotaucevnamotlipdceoradcteuinrge orntracineindgay(fanstdwEoIPrHk),hitowrsoeusldwbiteh
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Fhottrpfs:sur/t/hweawrbwd.eivevltiatytiplpsd/tp.ococropgmrea/ococmrfuornrsesmths/s/ ecocoactouuriestserses-s-o,lsiptstet/e/aimtuhstseurfamollilao-lwnenievnwge-lwzezeierabrlesaintsedp.-aencdt-iavsisiea#onfew-zez aland For further details/program on the course, see the following website.
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FallenStar:PreviouslyunbeatenPerthmareEnticingStar(yellow  1WinterbottomStakeswhennot inseason.
discipline . Horses with EGUS are known to have https://wwaw.svhetopdr.tceorms/ctoruidrsesl/econugrstehs,-lisast/aduestcrarleiaa-nseew-izneamlanadx-aimndu-amsia#australia https://wwowx.vyegtpedn.coump/ctoaukrsesa/cnodursteos-fliastt/aigusustreralisao-noewn-ezer.aland-and-asia#new-zealand
Michael Robinson on 0418 37th6is6c0o5ulodrpotentially reduce EIPH severity and thereby Another mrobinson@randlab.comim.apuro. ve race-day performance. scope after racing; albeit most of these horses will only have low to moderate
a b
6. (Ingcraredaese3thoer 4d)aEyIsPbHe.tween races for horses with severe 7. EIPH is not nece5ssarily a progressive disease, with EIPH
scope) after racing. formauflfaotridoanbbley IrnesoptehcetriveeqluyewstilrliahnavdeisEcIiPpHlindeisagsAuncouhsesadstarbfaterlriecalor’mascpilnegtianagnd.dipnoglo, 45% and 30%, EIPH has also been identified in sheowqjuminpersm, evedntiecrsi,nderessage horses,
Victorian racehorse trainer Mick Price recently struck out at Victorian Authorities calling for a “common sense” approach following the scratching ohfeornaebeorfrahnistbmaarriesrbaetthaeviboarroriner“bwehinegnhsehaevrileyfuinsesdeatosolonadde.sPpriticeebbelianmgoend injectable Progesterone”.
A staggering 68L of oral Altrenogest solution would be required to hreoarsche.thReacminingimNuSmWthCeErOap, eMurticPedtoesreVo’lfatnrdeynsborelocneent(l7y5amccgu) rfaotrealy500kg described the levels of Trenbolone found in formulations of Altrenogest as being “non-consequential”.
wRwAwN.DrDraLnAdlBabA.cUoSmT.aRuALIA SALES AND TEACUSHTNRAICLIANLOSWUNPEPD ORT AUSTRALIAN OWNED
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endurance racehorses, western speedmspoartnsuhofrasecst, lueirsuerre,and driving dverse
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John Dalton NSW/ACT Mobile 0404221776
Email john@randldab.com.au Andrew Grant QLD/NT MEMEmobaile 0a0ag4g4r2a6nt4@07ra1n1d7lab.com.au
grade of EIPH than horses racing in standard raCcinOg pXlates2. inhibitor 9. There is a diminishing response to repeated Lasix
AMAMloebxileMa0c4p21h1he8r2s9o1n0V1IC/TAS/SA Email alex@randlab.com.au
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shoes, they are more likely to have EIPH, and a t is a selective
Price stated in a recent radio interview that “The decision in New South Wales to have a threshold for Altrenogest is a good one and the business rolls on, no problem. The decision in Victoria is a poor one.”
Other Victorian trainers such as Colin Little, Ciaion Maher and Nigel Blackiston have also spoken out publicly in support of the ongoing use of APlrtoregneosgteersotncelairmeinjugsth“naot theeffepcrotipveosendoaulgtehr”n. ative of weekly injections of
Hypoaltrenogenaemia: a new cause of poor performance and misbehavior in fillies and mares.
www.randlab.com.au
FIGURE 1: Pyloric region of stomach (a) normal, (b) mild, (c) moderate, (d) severe ulceration.
AUSTRALIAN MADE
10.Hopoersraetsiothna) tmhayvebe5hamdo“rreolaikrelrystuorgbelerye”d (a=n‘dtieshMboaucnlkud”fabceturer of Superior Equine Veterinary Medicines & Supplements Sitnimintchees2ow0iw0n4adiptinpge tfoor al7osn/h8go5artfAtpeelrfrriaoecddinogRf oad, Chipping Norton 2170 Australia
www.randlab.com.au
QAUUASLTRITALYIA•N SOWENREVDICE • VAAUSLTUREAL•IANCMAARDE 1
Omeprazole based products remain the most effective treatment for gastric ulceration in the horse. Omeprazole is a proton-pump inhibitor which acts on the gastric parietal cells via the
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SUMMER 2018 NEWSLETTER
Welcome to Randlab’s TechTalk
In this issue Randlab’s Global Technical Director,IfDf yroMu wicohualdelliRkeobaninysionfno,rmloaotkiosnatboputitmhisisainrtgictlehecontact Randlab’s Global Technical Director/VTehtetreincahrniaicnal term for a “blecedhinrgo” isnEixcercmise usculoskeletal disorders.t Editor:
TafonhraembuwolalaictrinoinsstgesorofoiAdlllotrTwerenedongbtehoselot,ndwetheeactnthiodenr itothsfetyrpabrcecuianrmjseocrtuibnTltesreonrfdtoihorenael.adHirnoewnemrvogesirct, almost a year after the first report of a positive swab to Trenbolone of Altrenogest origin, there is still no consensus on the ongoing usage of Altrenogest amongst State Authorities. RtharecsinhgolNdSsWfohrasthinetrodeutceecdtioanneowfloTcreanlRboulloenoefRaancdingTwrehnidchioninetro(dwuhcens given in association with Altrenogest) of 1ng/mL in plasma or urine to agcacvoeuannt foinrtethrveiseew imonpuAriBtieCs.raRdaiocinegxpNlaSinWingCEwOhyPeNtSerWV’hlanddydsecriedceednttloy
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AUSTRALIAN MADE
Rebecca Puvanendran WA
EMEmobaile 0r0re4b2e0cc3a4@9r3a0n1dlab.com.au
Ian Saunders COMMERCIAL MANAGER EMEmobaile 0i0ia4n1.s6a7u7u7n7nd6d6e9rs9@1randlab.com.au
DGDGLr OMBicAhLaTeElCRHoNbIiCnAsLoLonDIBRVESCc TPOhDR
MEmobaiile 0m4r5o1b1in4s8o1n0@05r0andlab.com.au
Email mrobinson@randlab.com.au
. next
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fVeiactuoreia)P.aroltfehsosoursghTomprDoilvoernsg(Ceodrncelol Uunrsiversitoy)fahnidgFhradnkosAnedrNewSsA(LIDou’sisiana State University) and Dr Laura Nath (South Eastern pEeqrufoinremHaonscpeitanl,d should be performed 30-120 minutes be super thin so oxygen can enter the blood and carbon dioxide can exit
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track gallop with Lasix. AUSTRALIAN OWNED
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7/85 Alfred Road, Chipping Norton NSW 2170 Australia • Phone: (61-2) 9728 3505 • Fax: (61-2) 9728 4352 • Email: info@randlab.com.au
closely monitored for evidence of EIPH upon their return to racing following this surgery.
or galloping may mean the blood
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