Page 34 - ANZCP Gazette May 2023

Jabur et al. 7
Funding
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication
15. Sungurtekin H, Boston US, Orszulak TA, et al. Effect of cerebral embolization on regional autoregulation during cardiopulmonary bypass in dogs. Ann Thorac Surg 2000; 69(4): 1130–1134. 7
Jabur et al.
of this article: This work was supported by the transcranial
Doppler device was purchased with a grant from the Green
16. Brubakk AO, Duplancic D, Valic Z, et al. A single air dive 15. Sungurtekin H, Boston US, Orszulak TA, et al. Effect of
Funding
reduces arterial endothelial function in man. J Physiol cerebral embolization on regional autoregulation during
Lane Research and Educational Fund. The laptop required to
2005; 566(Pt 3): 901–906.
The author(s) disclosed receipt of the following financial run the transcranial Doppler software was purchased with a
cardiopulmonary bypass in dogs. Ann Thorac Surg 2000;
17. Jabur GN, Donnelly J, Merry AF, et al. A prospective
support for the research, authorship, and/or publication Joint Anesthesia Faculty of Auckland grant. The first author
69(4): 1130–1134.
of this article: This work was supported by the transcranial
observational study of emboli exposure in open ver- 16. Brubakk AO, Duplancic D, Valic Z, et al. A single air dive
received a PhD scholarship from the Green Lane Research Doppler device was purchased with a grant from the Green
sus closed chamber cardiac surgery. Perfusion 2021: reduces arterial endothelial function in man. J Physiol
and Educational Fund to conduct his research.
Lane Research and Educational Fund. The laptop required to
026765912110238, Jun 11, Online ahead of print. DOI: 2005; 566(Pt 3): 901–906.
ORCID iD
run the transcranial Doppler software was purchased with a
Joint Anesthesia Faculty of Auckland grant. The first author
17. J1a0b.u1r17G7N/0, 2D6o7n6n5e9ll1y21J,1M02e3rr8y97A.F, et al. A prospective
18. oCbzsoersvnaytkioanalMst,udSymoifelemwbsoklii ePx,poKsuirekpinatroipcekn vPe,r-et al.
received a PhD scholarship from the Green Lane Research
RefereOnRceCsID iD
1. SelGnehsazOwAan, NGSoJtatbeusmr hatntpsR:/F/o, rGcirde.ograg/M00A00,-0e0t0a2l-.1C26o4g-8n0i8ti8ve and neurologic outcomes after coronary-artery bypass surRgerfye.rNeenwceEsngl J Med 2012; 366(3): 250–257.
2. Shaw1. PSJe,lnBeasteOsAD, ,GCotaterstmlidagneRNF,EG,retgaalM. AN,eeutroal.oCgiocgnaintidve neuropasnycdhnoelourgoicloaglicmourtbcoidmiteys faoftlelorwcoinrognmarya-joartesruyrgbeypryas:s
sus closed chamber cardiac surgery. Perfusion 2021: Monitoring of cerebral autoregulation in head-injured
Ghazwan NS Jabur https://orcid.org/0000-0002-1264-8088 and Educational Fund to conduct his research.
026765912110238, Jun 11, Online ahead of print. DOI: patients. Stroke 1996; 27(10): 1829–1834.
surgery. New Engl J Med 2012; 366(3): 250–257. comparison of coronary artery bypass and peripheral
102: 145–151.
computational cardiopulmonary bypass. Perfusion
2. Shaw PJ, Bates D, Cartlidge NE, et al. Neurologic and vascular surgery. Stroke 1987; 18(4): 700–707.
20. Ho R, McDonald C, Pauls JP, et al. Aortic cannula 2020; 35(5): 409–416.
neuropsychological morbidity following major surgery: 3. Gottesman RF, Sherman PM, Grega MA, et al. Watershed
orientation and flow impacts embolic trajectories:
21. Heikkinen L. Clinically significant neurological disor-
comparison of coronary artery bypass and peripheral strokes after cardiac surgery: diagnosis, etiology, and out-
computational cardiopulmonary bypass. Perfusion
ders following open heart surgery. Thorac Cardiovasc Sur 2020; 35(5): 409–416.
vascular surgery. Stroke 1987; 18(4): 700–707. come. Stroke 2006; 37(9): 2306–2311.
1985; 33(4): 201–206.
21. Heikkinen L. Clinically significant neurological disor-
3. Gottesman RF, Sherman PM, Grega MA, et al. Watershed
22. Kaakkola S, Lehtosalo J, Laitinen LA. Changes in blood- ders following open heart surgery. Thorac Cardiovasc Sur
4. Lassen NA. Cerebral blood flow and oxygen consump- strokes after cardiac surgery: diagnosis, etiology, and out-
1b9r8a5in; 3b3a(4rr):ie2r01p–e2r0m6.eability to drugs in decompressed rats.
tion in cmomane. PSthroyksieo2l0R0e6v; 3179(59)9:;2390(62–)2:31813. –238.
5. Will4ie. CLKas,seTnzeNnAg.YC-eCr,ebFriaslhbelroJoAd,felotwal.aInndteogxryagteinvecroengsumlap--
22. KUanadkekrosleaaSB,LioemhtoedsaRloeJs,1L9ai8t2in;e9n(3L)A:.2C3h3a–n2g4e0s.inblood-
tion in man. Physiol Rev 1959; 39(2): 183–238.
tion of human brain blood flow. J Physiol 2014; 592(5):
brain barrier permeability to drugs in decompressed rats.
23. Chryssanthou C, Springer M, Lipschitz S. Blood-brain
5. Willie CK, Tzeng Y-C, Fisher JA, et al. Integrative regula- 841–859.
Undersea Biomed Res 1982; 9(3): 233–240.
and blood-lung barrier alteration by dysbaric exposure.
tion of human brain blood flow. J Physiol 2014; 592(5): 6. Joshi B, Ono M, Brown C, et al. Predicting the limits of
23. Chryssanthou C, Springer M, Lipschitz S. Blood-brain Undersea Biomed Res 1977; 4(2): 117–129.
and blood-lung barrier alteration by dysbaric exposure.
841–859.
cerebral autoregulation during cardiopulmonary bypass.
24. Helps SC, Parsons DW, Reilly PL, et al. The effect of gas
6. Joshi B, Ono M, Brown C, et al. Predicting the limits of
Undersea Biomed Res 1977; 4(2): 117–129.
Anesth Analg 2012; 114(3): 503–510.
cerebral autoregulation during cardiopulmonary bypass.
emboli on rabbit cerebral blood flow. Stroke 1990; 21(1): 24. Helps SC, Parsons DW, Reilly PL, et al. The effect of gas
7. Ono M, Joshi B, Brady K, et al. Risks for impaired cer- Anesth Analg 2012; 114(3): 503–510.
94–99.
emboli on rabbit cerebral blood flow. Stroke 1990; 21(1):
ebra7l.auOtonroegMu,laJotisohni Bd,uBrrinadgycKar,deitoapl.uRlmiskosnaforryibmypaairsesdancedr-
25. 9M4–it9c9h.ell SJ, Merry AF. Perspective on cerebral micro- 25. MemitbchoelliliSnJ,cMaredriraycAsuF.rgPersyp:escitgivneifoicnancetrpebrroabllmemicror- much
postoperbartailvaeustotroegkuel.aBtior nJ dAunrainegstchar2d0i1op2u; l1m0o9n(3ar)y: 3b9y1p–as3s9a8n.d
emboli in cardiac surgery: significant problem or much
ado about nothing? J Extra corpor Technol 2015; 47(1):
postoperative stroke. Br J Anaesth 2012; 109(3): 391–398. 8. Ono M, Brady K, Easley RB, et al. Duration and mag-
ado about nothing? J Extra corpor Technol 2015; 47(1): 10–15.
8. Ono M, Brady K, Easley RB, et al. Duration and mag- nitude of blood pressure below cerebral autoregulation
10–15.
nitude of blood pressure below cerebral autoregulation threshold during cardiopulmonary bypass is associated
threshold during cardiopulmonary bypass is associated with major morbidity and operative mortality. J Thorac
with major morbidity and operative mortality. J Thorac Cardiovasc Surg 2014; 147(1): 483–489.
Cardiovasc Surg 2014; 147(1): 483–489.
9. Chung EML, Banahan C, Patel N, et al. Size distribution
10.1177/02676591211023897.
19. Smielewski P, Lavinio A, Timofeev I, et al. ICM+, a
18. Czosnyka M, Smielewski P, Kirkpatrick P, et al. flexible platform for investigations of cerebrospinal Monitoring of cerebral autoregulation in head-injured
dynamics in clinical practice. Acta Neurochir Suppl 2008; patients. Stroke 1996; 27(10): 1829–1834.
102: 145–151.
19. Smielewski P, Lavinio A, Timofeev I, et al. ICM+, a
20. fHleoxibRle, MplactDfoormnalfdorCi,nvPeastuiglsatiJoPn,setofalc.erAeborotsipcincaalnnula d o y r n i e a mn t i c a s t i i n o n c l i n a n i c d a l p f l r o a c w t i c i e m. A p c a t a c Nt s e u e r mo c b h i o r l S i u c p p t r l a 2 0 j e 0 c 8 t ; o r i e s :
9. Chung EML, Banahan C, Patel N, et al. Size distribution of air boufbabirlebsuebnbtlesrienngtetrhinegbtrhaeinbrdaiunrdinugrincgarcdairadciascusrugregreyr.y. PLoS OPnLeo2S0O1n5e; 1201(45;):10e(041)2: e20116262.166.
10. Gorman D, Browning DM., Parsons DW., et al. The dis- 10. Gorman D, Browning DM., Parsons DW., et al. The dis-
tribution of arterial gas emboli in the pial circulation. tribution of arterial gas emboli in the pial circulation.
SPUMS J 1987; 17(3): 101–116. SPUMS J 1987; 17(3): 101–116.
11. Hills BA, James PB. Microbubble damage to the blood- 11. Hills BA, James PB. Microbubble damage to the blood-
brain barrier: relevance to decompression sickness. brain barrier: relevance to decompression sickness.
Undersea Biomedical Research 1991; 18(2): 111–116. Undersea Biomedical Research 1991; 18(2): 111–116.
12. Nossum V, Koteng S, Brubakk AO. Endothelial damage 12. NossumbyVb,uKbboltesnign tSh,eBprulbmaoknkarAyOar.teErnydoof thelpiaigl.dUanmdeargsea
by bubbHlyepseirnb Mthedp1u9l9m9;o2n6a(1r)y: 1a–r8te. ry of the pig. Undersea 13. Suzuki A, Armstead SC, Eckmann DM. Surfactant
Hyperb Med 1999; 26(1): 1–8.
reduction in embolism bubble adhesion and endothelial
13. Suzuki A, Armstead SC, Eckmann DM. Surfactant
damage. Anesthesiology 2004; 101(1): 97–103. reduction in embolism bubble adhesion and endothelial
14. Fok H, Jiang B, Chowienczyk P, et al. Microbubbles shunt- damage. Anesthesiology 2004; 101(1): 97–103.
ing via a patent foramen ovale impair endothelial func- 14. Fok H, Jiang B, Chowienczyk P, et al. Microbubbles shunt-
tion. JRSM Cardiovasc Dis 2015; 4: 2048004015601564. ing via a patent foramen ovale impair endothelial func-
tion. JRSM Cardiovasc Dis 2015; 4: 2048004015601564.
31 MAY 2023 | www.anzcp.org
Appendix Appendix
Notatiion
IQR – IQR –
Abbreviations and acronyms Abbreviations and acronyms
CCloSse–dchambersurgery
Closed chamber surgery CI –
Confidence interval CI –
CoPnBf–idence interval
Cardiopulmonary Bypass CPB –
Cardiopulmonary Bypass
MAMP –AP –
Mean arterial pressure Mean arterial pressure
MeaMnxve–locityindex
Mean velocity index OCS –
Open chamber surgery OCS –
SD –Open chamber surgery
Standard deviation SD –
CABG – CABG –
MCA – MCA –
Coronary artery bypass grafting
Coronary artery bypass grafting Middle cerebral artery
CBFv –
md –
CBFv –
Cerebral blood flow velocity
md –
mean difference
Cerebral blood flow velocity CCS –
mean difference Mx –
InteIrnqutearqtiulearatnilgeerange
Middle cerebral artery
TCD –
Standard deviation
Transcranial Doppler TCD –
Transcranial Doppler