Page 138 - Ebook-Book JCMS 2025

Efficacy of Lavender Aroma Inhalation for Pain and Anxiety
Relief During Endometrial Sampling in Women Aged at Least
35 Years Old with Abnormal Uterine Bleeding; Randomized
Single-blind Controlled Trial
Natnaree Phosrinak, Sawanya Benchahong, Densak Pongrojpaw*
Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University
*Corresponding Author E-mail: pongrojpaw@gmail.com
Objective: Methods: Results: Abstract
To evaluate the efficacy of lavender essential oil aroma inhalation for pain and anxiety relief
in endometrial biopsy procedure.
The study was conducted at Gynecology Outpatient Clinic, Thammasat University Hospital,
Pathum Thani, Thailand between May 2024 and March 2025. The study included patients
aged 35 years or more who had abnormal uterine bleeding. 140 patients were randomly
allocated to either receive lavender essential oil aroma inhalation (study group) or sterile
water inhalation (control group). Assessment of pain severity and anxiety level were
evaluated using a visual analogue scale (VAS,VFAS) score at 3 time-points; P0, A0, P1, A1,
P2, and A2.
In total, 140 patients were screened and were randomly allocated to either receive lavender
essential oil aroma inhalation (study group, n = 70) or sterile water inhalation (control
group, n = 70). Lavender essential oil aroma inhalation can reduce pain both during the
endometrium sampling procedure (P1) and 15 minutes after the procedure significantly
(P2) compare to sterile water inhalation (P = 0.03 and 0.004). Expected severe pain score
before the procedure were reported fewer in study group (26 vs. 42, P = 0.022). And 15
minutes after the procedure, severe pain also reported fewer in study group (20 vs 36 P
= 0.017). There was no significant difference in severe pain during the procedure in both
group (47 vs. 36 P = 0.078) Lavender essential oil aroma inhalation can reduce severe pain
significantly (from 36 during the procedure to 20 in 15 minutes after the procedure). The
anxiety score 15 minutes after the procedure decrease significantly in lavender essential
oil inhalation group (P = 0.036). But the severity of anxiety score reported insignificantly
change in both group at all time point (expected, during the procedure, and 15 minutes
after).
Conclusions: Lavender essential oil aroma inhalation is effective in pain relief during and after the
endometrial sampling procedure and is effective in anxiety relief after the procedure.
Moreover, Lavender essential oil aroma inhalation can reduce severity of pain after the
procedure significantly.
136 Joint Conference in Medical Sciences 2025