Page 10 - research hubs
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Reproductive
Health Hub
Studying Diseases in Order to Preserve Fertility
The members of the Reproduction Hub have come together to find answers to vital issues of reproduction: issues largely unaddressed by the research establishment, despite their long-term impact on the future of various population sectors.
Hub researchers in the fields of immunology, microbiology, genetics, and epidemiology, together with clinicians in reproductive medicine, have determined specific focal points for their endeavors, such as fertility preservation in the care of adult male patients, as well as pre-adolescent male cancer patients who are at risk of premature gonadal failure.
Both environmental factors and genetics can play a key role in reproduction. Each individual’s DNA is unique, but we exist within an environment that is comprised of microbes with different DNA. Our bodies are colonized by different microbes depending on various genetic and environmental factors, and these microbial populations change over time. Hub researchers believe that these microbiomes can affect individuals, including fetuses.
Building on existing strengths and employing the vast array of data and resources available at both the FOHS and at the affiliated Soroka University Medical Center, and working with populations where consanguineous marriages (between close blood relations) are still common, the Hub offers ideal prospects for coordinated research on both clinical and basic science levels.
Pregnancy is seen as a window of opportunity to detect future mother and child diseases, and every woman who is admitted to Soroka for childbirth is now asked to participate. Hub researchers have begun to build a biobank to house maternal serum, amniotic fluid, and placentas, together with clinical and environmental data. All of these will be used for research and evaluation, and should lead to the development of improved intervention strategies.
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