Page 11 - research hubs
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Translational Infectious Diseases Hub
Understanding Microbiomes and Their Role in Infection to Transform Public Health
The Translational Infectious Diseases Hub seeks to revolutionize public health policy and management via innovative One Health/EcoHealth approaches.
The paradigm of One Health/EcoHealth is underpinned by the fact that all living organisms are comprised of microbiomes, and as such, humans, animals, and the environment are interdependent. Microbiomes exist as ecological communities that are interconnected and impact one another.
Close collaborative ties between basic scientists, physicians, and clinical and environmental microbiologists allow Hub members to collectively investigate the role of microbiomes in the spread of infection, and the processes by which they develop resistance to infection.
Some of the questions under investigation include: Are there differences in microbiome makeup between those from poor, rural areas and those with affluent urban lifestyles? How do bacteria develop resistance? What are the links between hospital-resistant bacteria and bacteria in other environments? Can the study of the microbiome be used to counter drug resistance in bacteria? How can we translate our knowledge of microbiology into effective public health policy?
The answers to these and other questions have implications for millions of people living in different environments with exposure to conditions promoting specific diseases, such as small agricultural communities suffering from brucellosis contracted from unpasteurized milk, or children in urban locales who suffer from respiratory infections due to acute air pollution.
The studies undertaken by the Translational Infectious Diseases Hub will inform new public policy in a wide range of fields, and will help shape Israel’s overall health and the “health equality” of its populace.
The Translational Infectious Diseases Hub will use a One Health/EcoHealth approach to improve health, security, and resilience within Israel’s borders and beyond. Its members aim to make major contributions in the development of new protocols in hospitals, new standards for the design of both rural and urban infrastructure projects; improved air pollution guidelines; and more effective responses to biological and chemical threats.

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