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ROAD; Titration to optimal albuminuria lowering using ARB affords better renal protection in non-diabetic renal disease irrespective of blood pressure
160 140
120 100
80
60 0
40 30 20 10
0
Losartan convent dose: 50 mg Losartan titrated dose: 117.7 mg
Systolic Blood pressure
Diastolic Blood pressure
12 24 36
0 6 12 18 24 30 36
Follow-up (mo)
Hou et al; JASN 2007
Blood Pressure (mmHg)
Primary Composite End point (%)