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Perhaps one should mention in here is Claude Bernard. Claude Bernard was the one who defined that the kidneys don't have simply the role of excreting poisons but regulating our interior milieu. He was unhappily married to a wife who was constantly complaining that he didn't make enough money, but he made what is more important we think; fame instead.
By the 19th century, uremia is fairly well understood From that point on, the knowledge literally
explodes. If you look at uremia at the end of the 19th Century, this lecture very well describes the acidosis of uremia, the creatinemia, the phosphate elevation, and so forth. This is simply a lecture like the one I am giving here to you today, given 100 years ago in London.
L’uremia
Claude Bernard
Quintaliani


































































































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