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The Ādam Paradox Hypothesis 247
Phase III (10–20 Years): Consolidation and Falsification
Goals: Subject APH to decisive tests.
Subject the Adam Paradox Hypothesis (APH) to decisive, large-scale tests that
either confirm or falsify its predictions. By this stage, the research program
moves from feasibility (Phase I) and integration (Phase II) to final judgment:
does APH withstand full scientific scrutiny?
Genomics
What to Do
1. Determine whether ignition-linked regulatory sweeps cluster sharply at
~70kya or scatter randomly across 300–50kya.
Using the massive sequencing databases built in Phase II, this step resolves
whether selective sweeps truly converge near the ignition window.
This is a statistical “
yes/no” test: clustering = ignition; scattering =
gradualism.
2. Publish definitive comparative maps of modern vs. archaic regulatory
architectures.
Create a complete atlas of how modern humans differ from Neanderthals,
Denisovans, and earlier hominins in terms of regulatory networks.
This map identifies exactly which regions of DNA were unique to Homo
sapiens and whether they plausibly underpin symbolic cognition.
Tools
Global genomic repositories with >100,000 genomes, covering worldwide
populations.
Machine learning pipelines capable of detecting fine-grained sweep patterns
across time and geography.
Comparative epigenomics (measuring regulatory gene expression changes,
not just DNA sequence differences) for archaic vs. modern samples.
3D genome architecture mapping (Hi-C technology) to see how regulatory
regions physically interact in the nucleus.