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Study on alternations in immune, inflammatory and endocrine responses in Indian diabetic patients infected with SARS-CoV-2 and its clinical consequences
COVID-19 lung ultrasound database: A study by IIT Palakkad
Understanding the efficacy of existing drug molecules on COVID-19 through an interactive pathway: A deep learning-based predictive model
Study on SARS-CoV-2 Delta variant replication and immune evasion mechanism
IIT Delhi, AIIMS New Delhi and Addverb co-develop telerobotic ultrasound system during COVID-19 pandemic times
Study on the impact of environmental indicators on the COVID-19 pandemic in Delhi
COVID-19 pandemic: Insights into molecular mechanisms leading to sex-based differences in patient outcomes
IIT Palakkad made a roadmap for investigation on the long-term effects of COVID-19 in the context of airways diseases
Second round statewide survey for estimation of the burden of active infection and anti- SARS-CoV-2 IgG antibodies in the general population of Karnataka, India
Identification of COVID-19 prognostic markers and therapeutic targets through meta- analysis and validation of Omics data from nasopharyngeal samples
Fighting COVID-19 viral variants with a heat-tolerant vaccine
IIT, BHU to use drug repurposing strategy to target SARS-CoV-2
main protease for treating COVID-19
The research group of Prof. Vikash Kumar Dubey from IIT, BHU, is working on developing new drug candidates against SARS-CoV-2 by exploring DrugBank (DrugBank is a database of FDA approved drug compounds) database compounds as an inhibitor of SARS-CoV-2 main protease, a key enzyme required for SARS-CoV-2 assembly and multiplication.
Taking advantage of available crystal structure of the SARS-CoV-2 main protease, a structure- based inhibitor design will be made by the researchers from the available FDA approved drugs compounds in the DrugBank database.
Subsequently, experimental validation of the designed inhibitor(s) on recombinant SARS-CoV-2 Mpro Protein will be carried out. Various inhibitor parameters will be calculated to establish
VOL. IV ISSUE 10
VIGYAN PRASAR 14
COVID-19 SCIENCE & TECHNOLOGY EFFORTS IN INDIA