Page 41 - Covid Special Issue

COVID-19-related publications & pre-prints from NIBMG
Several COVID-19-related publications/pre-prints had been published by NIBMG. There are eight publications on COVID-19 and these publication/pre-prints are as follows:
1. SARS-CoV-2 mutation 614G creates an elastase cleavage site enhancing its spread in high AAT-deficient regions;
2. Association of clade-G SARS-CoV-2 viruses and age with increased mortality rates across 57 countries and India;
3. Host response to SARS-CoV-2: Insight from transcriptomic studies;
4. Dynamic dysregulation of IL-6 and genes functional in NETosis, complement and coagulation
in severe COVID-19 illness;
5. SARS-CoV-2 infection in India bucks the trend: trained innate immunity?
6. PAN-INDIA 1000 SARS-CoV-2 RNA Genome Sequencing Reveals Important Insights into
the Outbreak;
7. Global cataloguing of variations in untranslated regions of viral genome and prediction
of key host RNA binding protein-microRNA interactions modulating genome stability in
SARS-CoV-2;
8. Phylogenetic clustering of the Indian SARS-CoV-2 genomes reveals the presence of distinct
clades of viral haplotypes among states;
9. Mutations in SARS-CoV-2 Viral RNA Identified in Eastern India: Possible Implications for
the 1 Ongoing Outbreak in India and Impact on Viral Structure and Host Susceptibility;
10. Global Spread of SARS-CoV-2 Subtype with Spike Protein Mutation D614G is Shaped by
Human Genomic Variations that Regulate Expression of TMPRSS2 and MX1 Genes; and
11. Analysis of RNA Sequences of 3636 SARS-CoV-2 Collected from 55 Countries Reveals
Selective Sweep of One Virus Type.
Website Link:
https://www.nibmg.ac.in/academic/Covid19/COVID%2019%20Papers%20and%20Preprints%20from%20 NIBMG.pdf
Research Publications from RCB, Faridabad on COVID-19
Regional Centre for Biotechnology (RCB) printed research publications on COVID-19 to reach out to the people. These publications had details about effects of Coronavirus and COVID-19 on the human body. There are three publication/research papers that were published during pandemic which focuses on the following:
1. Ritonavir may inhibit exoribonuclease activity of nsp14 from the SARS-CoV-2 Virus and potentiate the action of chain-terminating drugs;
2. Vitamin B12 may inhibit RNA-dependent- RNA polymerase activity of nsp12 of the COVID-19 Virus; and
3. Loss of Smell and Taste: Potential of Using Them as Markers for Early Detection of Covid-19.
Website Link:
https://www.rcb.res.in/index.php?param=quicklinks/ COVID-19
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