Page 75 - Simplicity is Key in CRT

Rhythm Society (AHA/ACC/HRS) guideline definition (9,10), the Multicenter Automatic Defibrillator Implantation with Cardiac Resynchronization Therapy (MADIT-CRT) trial and the REsynchronization reVErses Remodeling in Systolic Left vEntricular dysfunction (REVERSE) trial LBBB definition (6,7), and the LBBB definition proposed by Strauss et al.(11) An example ECG is shown in figure 1.
Figure 1. Example ECG with classification of LBBB according to multiple definitions.
Example ECG meeting criteria for ESC and MADIT LBBB definitions. However, the presence of a Q wave in leads I and aVL, and the absence of notching/slurring in two consecutive leads preclude it from qualifying as LBBB according to AHA/ACC/HRS and Strauss definition.
AHA/ACC/HRS = the American Heart Association/American College of Cardiology Foundation/Heart Rhythm Society, ESC = European Society of Cardiology, MADIT = the Multicenter Automatic Defibrillator Implantation with Cardiac Resynchronization Therapy trial.
Clinical study end point
The primary endpoint was a combination of LV assist device implantation (LVAD), cardiac transplantation and all- cause mortality. Information was obtained from hospital records, linked to municipal registries. Outcome data was collected until end of follow-up December 2015.
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