Page 27 - Labatt Brain Tumour Research Centre Annual Report 2022 to 2023

Donovan LK, Taylor MD. Amplifying natural antitumor immunity for personalized immunotherapy. Cell Research. 2022 Jun;32(6):505-506.
Gaebe K, Li AY, Park A, Parmar A, Lok BH, Sahgal A, Chan K, Erickson AW, Das S. Stereotactic radiosurgery versus whole brain radiation therapy in patients with intracranial metastatic disease and small cell lung cancer: a systematic review and meta-analysis. The Lancet Oncology. 2022 Jul 1;23(7):931-939.
Hamed AA, Kunz DJ, El-Hamamy I, Trinh QM, Subedar OD, Richards LM, Foltz W, Bullivant G, Ware M, Vladoiu MC, Zhang J, Raj AM, Pugh TJ, Taylor MD, Teichmann SA, Stein LD, Simons BD, Dirks PB. A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours. Nature Communications. 2022 Jul 19;13(1):4178.
Henderson JJ, Das A, Morgenstern DA, Sudhaman S, Bianchi V, Chung J, Negm L, Edwards M, Kram DE,
Osborn M, Hawkins C, Bouffet E, Cho YJ, Tabori U. Immune checkpoint inhibition as single therapy for synchronous cancers exhibiting hypermutation: An IRRDC study.
JCO Precision Oncology. 2022 Mar;6:e2100286.
Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudière-Morrison L, Mercier AL, Shokouhian M, Suárez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Bérubé P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon
J, Grajkowska WA, Loukides J, Dirks P, Fèvre-Montange
M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, López-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Lolascon A, Ferrucci
V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguía P, Pérezpeña M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman
CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD. Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Sep;609(7929):1021-1028.
Ishwar D, Haldavnekar R, Bo T, Das S, Venkatkrishnan K. Glioblastoma-associated natural killer cell EVs generating tumour-specific signatures: non-invasive GBM liquid biopsy with self-functionalized quantum probes. ACS Nano. 2022 July 11, 16(7):10859-10877.
Li A, Gaebe K, Jerzak K, Cheema P, Sahgal A, Das S. Intracranial metastatic disease: present challenges, future opportunities. Frontiers in Oncology. 2022 Mar 7;12.
Lim Fat MJ, Macdonald M, Lapointe S, Climans SA, Cacciotti C, Chahal M, Perrault S, Tsang D, Gao A, Yip S, Keith J, Bennett J, Ramaswamy V, Tabori U, Das S, Hawkins C. Molecular testing for adolescent and young adult central nervous system tumours: A Canadian Guideline. Frontiers
in Oncology. 2022 Sept 23;12L960509.
McCoy LG, Brenna CTA, Chen S, Das S. Big decisions on a small scale: from evidence-based medicine to personalized medicine. AJOB Neuroscience. Apr-Jun 2022;13(2):132-134.
Mushtaq N, Mustansir F, Minhas K, Usman S, Qureshi BM, Mubarak F, Bari E, Enam SA, Laghari AA, Javed G, Shamim S, Darbar A, Abbasi AN, Kirmani S, Resham S, Bilal A, Hamid SA, Zia N, Shaheen N, Wali R, Ghafoor T, Imam U, Maaz AUR, Khan S, Laperriere N, Desbrandes F, Dirks P, Drake J, Huang A, Tabori U, Hawkins C, Bartels U, Ramaswamy V, Bouffet E. Building the ecosystem for pediatric neuro-oncology care in Pakistan: Results of
a 7-year long twinning program between Canada and Pakistan. Pediatric Blood & Cancer. 2022 Apr 28:e29726.
Nassiri F, Wang JZ, Au K, Barnholtz-Sloan J, Jenkinson MD, Drummond K, Zhou Y, Snyder JM, Brastianos P, Santarius T, Suppiah S, Poisson L, Gaillard F, Rosenthal M, Kaufmann T, Tsang DS, Aldape K, Zadeh G; Consensus core clinical data elements for meningiomas. Neuro-Oncology. 2022 May 4;24(5):683-693.
Nobre L, Hawkins C. Liquid biopsy for pediatric brain tumor patients: is it prime time yet? Neuro-Oncology. 2022 May 27:noac140.
Siddaway R, Canty L, Pajovic S, Milos S, Coyaud E, Sbergio SG, Vadivel Anguraj AK, Lubanszky E, Yun HY, Portante A, Carette S, Zhang C, Moran MF, Raught B, Campos E, Hawkins C. Oncohistone interactome profling uncovers contrasting oncogenic mechanisms and identifes potential therapeutic targets in high grade glioma. Acta Neuropathologica. 2022 Nov;144(5):1027-1048.
Siddaway R, Milos S, Coyaud É, Yun HY, Morcos SM, Pajovic S, Campos EI, Raught B, Hawkins C. The in vivo interaction landscape of histones H3.1 and H3.3. Molecular & Cellular Proteomics. 2022 Oct;21(10):100411.
Siddaway R, Milos S, Vadivel AKA, Dobson THW, Swaminathan J, Ryall S, Pajovic S, Patel PG, Nazarian J, Becher O, Brudno M, Ramani A, Gopalakrishnan V, Hawkins C. Splicing is an alternate oncogenic pathway activation mechanism in glioma. Nature Communications. 2022 Jan 31;13(1):588.
Zagozewski J, Borlase S, Guppy BJ, Coudière-Morrison L, Shahriary GM, Gordon V, Liang L, Cheng S, Porter CJ, Kelley R, Hawkins C, Chan JA, Liang Y, Gong J, Nör C, Saulnier O, Wechsler-Reya RJ, Ramaswamy V, Werbowetski-Ogilvie TE. Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression. Communications Biology. 2022 Jul 14;5(1):697.
Zuccato JA, Patil V, Mansouri S, Liu JC, Nassiri F, Mamatjan Y, Chakravarthy A, Karimi S, Almeida JP, Bernat AL, Hasen M, Singh O, Khan S, Kislinger T, Sinha N, Froelich S, Adle-Biassette H, Aldape KD, De Carvalho DD, Zadeh G. DNA Methylation based prognostic subtypes of chordoma tumors in tissue and plasma. Neuro-Oncology. 2022 Mar 12;24(3):442-454.
Zhang Y, Dho SE, Othman K, Simpson CD, Lapierre J, Bondoc A, McGlade CJ. Numb exon 9 inclusion regulates Integrinβ5 surface expression and promotes breast cancer metastasis. Oncogene. 2022. 41(14), 2079–2094.
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ON THE BACK COVER
Group photograph of the generous supporters and attendees of the 22nd annual Bunzl Golf Tournament fundraising event held in July 2022.