Page 4 - Randlab TechTalk Newsletter Issue 2
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RANDLAB TechTalk
Key Points
HA can be used effectively either intravenously or intra-articularly.
HA intra-articularly can be used alone or in combination with corticosteroids.
HA provides anti-inflammatory and analgesic properties in appropriate cases.
Exogenous HA can enhance the quality of joint fluid and improve ongoing production of natural HA.
Not all exogenous HA’s are the same. There are considerable differences in viscosity, protein levels, purity, molecular weight and safety and efficacy between different brands.
Regular use of intra-articular HA can greatly improve joint function in the longer term.
The combined use of HA and corticosteroids is still the gold standard by which other joint treatments are judged.
HA administration when using
a high quality HA either intra- articularly or intravenously is known to be a safe, reliable and cost- effective means of assisting in the management of joint disease.
HA used following joint surgery in appropriate cases can decrease the amount of synovial effusion and increase flexibility within the joint.
Compared to many newer treatments for joint disease, HA is still very effective, safe, simple to use and cost-effective.
Intra-articular HA and
Corticosteroids
(ensure compliance with event rules)
Dose
20 mg HA and
Either
20mg Dexamethasone
OR
10-20 mg Triamcinolone
OR
10 -40 mg Triamcinolone and
15 mg Dexamethasone
OR
15 mg Voren Depot (potential prolonged excretion)
OR
40-120mg Depomedrol (potential prolonged excretion)
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