Page 9 - D'Conner PRODUCT catalogue

FORMULATION:
Each vial contains Cefoxitin 1 g Powder for Injection.
DESCRIPTION:
It is used to treat bacterial infections and may be used prior certain surgeries to prevent
infections. It belongs to the class known as cephalosporin antibiotics. It works by killing bacteria
or preventing their growth. However, this medicine will not work for colds, flu, or other virus
infections.
MECHANISM OF ACTION:
• The bactericidal action of cefoxitin results from inhibition of cell wall synthesis.
INDICATIONS:
 For the treatment of peritonitis and intra-abdominal intrapelvic infections, septicemia,
endocarditis, gynecological, respiratory tract, bone and joint, skin and soft tissue
infections, urinary tract infections including uncomplicated gonorrhea
 It is special for its ability to treat certain anaerobic and mixed aerobic-anaerobic
infections, such as pelvic inflammatory disease and lung abscess.
DOSAGE AND ADMINISTRATION:
 Dosage should be determined by susceptibility of the causative organisms, severity of
infection, and the condition of the patient. The total daily dosage should not exceed 12
grams. The higher dosages should be used for more severe or serious infections.
Adult:
 The usual adult dosage range is 1 gram to 2 grams every six to eight hours.
 i.e. Uncomplicated: 1g every 6–8hrs. Moderately severe to severe: 1g every 4hrs or 2g
every 6–8hrs. Max 2g every 4hrs or 3g every 6hrs.
Pediatric Patients:
 ≥ 3 months: 80 to 160 mg/kg of body weight per day divided into four to six equal
doses.
Prior to Surgery:
 It should be given ½ to an hour before the operation to achieve effective levels during
the procedure.
Prophylactic administration should usually be stopped within 24 hours
WARNINGS/PRECAUTIONS:
 Do not take if you have known Allergy to Penicillin and diagnosed with Renal
impairment or GI disease (esp. colitis).
ADVERSE REACTIONS:
 Local reactions, rash, pruritus, drug fever, GI upset, anaphylaxis, blood dyscrasias,
elevated liver enzymes.
INTERACTIONS:
 Do not take with Aminoglycosides and probenecid
 Laboratory results: it may cause false (+) Clinitest and interference with creatinine
tests.
PREGNANCY CATEGORY: B
MANUFACTURED BY:
Phil Inter Pharma Co. LTD., VIETNAM
IMPORTED BY:
Grovic Pharma Inc., Pandacan, MANILA
DISTRIBUTED BY:
Grovic Pharma Inc., Pandacan, MANILA