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Physical activity and energy restriction alters gene expression in the tumor microenvironment
Tumors 0.05-2.0 cm3 Day 35 post tumor implantation
Turbitt, et al. Cancer Prevention Research. 2019;12(8):493-506.
Physical activity and energy restriction increases CD8+ T cell infiltration and reduces the infiltration of MDSCs in the tumor
microenvironment Tumors 0.05-2.0 cm3
30 p<0.05 40 p<0.05 6
20 30 4
20
10 10 2
p<0.05 p<0.05
000 SESDED+PAAL+SAELDSE+DPEARPA+ER SESDE+DPAPAAL+SAELDS+EPEDARP+AER SESDED+PAAPLA+SAELSDE+DPEARP+AER
AL ER AL ER
AL ER
Turbitt, et al. Cancer Prevention Research. 2019;12(8):493-506.
157
% of CD8+ cells/tumor
% of Gr1+/CD11b+ cells/tumor
CD8:total MDSC ratio

