Page 277 - Blog Posts v1

For larger targets, which cool more slowly but achieve a lower peak temperature, a longer heating time also result in the required denaturation.
Clinically, this means that a higher degree of success should occur with longer pulses compared with short pulses. Of particular importance is the understanding that increasing the applied fluence will rapidly increase the amount of tissue damage due to the exponential increase in protein denaturation with temperature.
In reality, this means that it is always better to extend the pulsewidth rather than increase the fluence, if you want to use more energy in any particular situation! This is a more controllable method of increasing the tissue damage.
Please note: pulse duration is the same as pulsewidth is the same as the pulse length!! If you have any queries about this stuff please leave me a message.
Ciao, Mike.
Mike’s Blog Posts 277