Page 247 - Chapter 3 - Laser/IPL Hair Removal
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                   Chapter 3 – Fundamentals of Laser/IPL Hair Removal 2nd Edition
Further, whilst researchers never actually state this (as yet), it appears that repeated disruptions of this type, may lead to complete breakdown of the growth cycle. However, further clinical research is needed to confirm this hypothesis.
Clinical Studies using Low Fluence Devices
A number of studies were carried out using a range of low fluence, home-use devices (Emerson and Town):
  Wavelength
   Fluence
   Pulsewidth
   No of sessions
   Skin Type
   Hair reduction
   Ref
        400-1200 6.25- 6.45
400-1200 2-7.5
530-1200 12.5-13
530-1200 16
Silk’n <5
35 1 to 3
35 Up to 10
30 1
30 1 to 5
- 6
-
1 to 4
3
-
1 to 4
27%
35 - 50%
41 - 45%
-
40-75%
Goldberg & Silapunt
Levenburg and Ha’rofeem
Omi and Clement
Ancona
Alster and Tanzi
  400-1200
   4-6.5
   35
   4 to 9
   2, 3
   77% (50 to 90%)
   Adatto
   400-1200
   2-7.5
   35
   3
   1 to 4
   55%
   Rohrer and Touma
   530-1200
   11
   30
   1
   1, 2
   60.4%
   Clement
   530-1200
   11.6
   35-45
   Up to 10
   5, 6 “Indian”
   >50%
   Vedamurthy and Town
   600-950
   2 - 15
   15
   2 to 3
   1 to 6
   70-85%
   Nuijs et.al.
 Table 49 - Clinical studies using low fluence HUDs
These results show that low fluence devices can reduce hair significantly, across all skin types, with a range of fluences. In particular, Marijke et.al. defined five ‘classes’ of HF thermal damage observed in their study with a diode laser applying fluences between 1.7 and 26.4 J/cm2:
Class I Minimal damage. Occurs at 1.7 J/cm2. No apoptosis observed.
Class II Reduction of the DP size. A “few” apoptotic cells in the DP and ORS occasionally observed.
________________________________________________________________________ 247 Chapter 3, Ed. 2.0 Laser/IPL Hair Removal
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