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ADAPTOGENS are a loose family of nutritional supplements that are thought to help the body “adapt to stress.” Their mechanisms of action all differ but their goal is the same, to restore the body to homeostasis this is achieved by stabilizing the HPA-axis.
Magnolia Bark has two main components, honokiol, and magnolol, which have been a part of traditional Chinese medicine for centuries. Research has shown that Magnolia Bark can pass through the brain-blood barrier and is neuroprotective. Its mechanism of action is through the down-regulating of Glutamate receptors, which overstimulate the mind and body. It also works through the Endocannabinoid system in a similar manner to CBD. Animal studies have shown that Magnolia Bark has a direct regulating effect on the HPA-axis which reduces the negative effects of stress and helps with the associated depression. A typical dosage would be 250 mg/day an hour before bed. An additional 250 mg can be used for break through anxiety.
Roseroot (Rhodiola rosea) has been shown in research to reduce cortisol and down- regulate the HPA-axis. Roseroot (Rhodiola rosea) has been shown in research to reduce cortisol and down-regulate the HPA-axis. It has the benefit of working within 30 minutes and lasting for up to six hours making it one of the most effective adaptogens. Rhodiola dosage at 600 mg/day has been shown to reduce burnout and stressed induced fatigue.
Ashwagandha is unique as an adaptogen because its mechanism of action involves modulating the GABA receptors to promote a sense of calm and reduce triggering the HPA-axis. Research has shown that a dosage of 300 mg twice a day is helpful for stress reduction and weight loss.
The examples above are only a sample of the adaptogens available. Adaptogens have been linked to numerous health benefits: improved cognitive function, sleep, energy,
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