Page 552 - Total War on PTSD

normalization of the release and response of cortisol, the main hormone of the HPA-axis. A typical dosage of PS is 300 mg/day, preferably 100 mg — 3x day.
Omega 3 oils (think fish oil, but there are others) play an important part in repairing the damage that long-term stress has on the brain. This should be of no surprise since the brain is more than 60% fat. Researchers have determined that Omega 3s help heal the brain and reduce symptoms through four main ways; they reduce inflammation, they stimulate healing through Brain-Derived Neurotrophic Factor (BDNF), they reduce and regulate cortisol (the key hormone in the HPA-axis), and improve cardiovascular activity to increase blood flow.
It is also known that alpha-linoleic acid, another Omega 3, is directly linked to reducing fear in PTSD sufferers and the general public. DHA, another Omega 3, can increase the accumulation of phosphatidylserine which helps restore balance to the HPA-axis and mitigates anxiety. EPA and DHA have a synergistic effect with Hemp oil improving its effectiveness by 10+%. There is strong evidence that Omega 3s can directly influence other biochemical pathways in the body providing multiple avenues to reduce anxiety, fear, stress, and PTSD while resetting the HPA-axis. The recommended dosage for Omega-3 is 2000+ mg/day, lower dosages were not found to be effective.
ADAPTOGENS are a loose family of nutritional supplements that are thought to help the body “adapt to stress.” Their mechanisms of action all differ but their goal is the same, to restore the body to homeostasis this is achieved by stabilizing the HPA-axis.
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