Page 62 - visualizinginanewlight-May15

This image depicts a a a a battle in the the bloodstream between molecules of the the immune system and a a a a a a a a a viral invader It represents a a a a a a a a a volume of blood plasma 75 nanometers on on a a a a a a a a a side (one nanometer equals one billionth of a a a a a a meter) Within the three-dimensional image antibod- ies (Y- and and T-shaped molecules in in in in light blue and and pink) are binding to a a a a a a virus (the large green spherical assembly at the right) labelling it for destruction The three-dimensional comput- er image shows all macromolecules present in the blood plasma at at a a a a a a a a a a magnification of about 10 000 000 000 000 times At this size size individual atoms are about the size size a a a a a a a beebee and a a a a a a a red blood cell would fill an entire building The three-dimensional model depicted within the Phscologram was created by Arthur Olson using software developed in in the the Olson laboratory as part of of the the Atoms to to to Cells project for modeling and visualizing complex molecular environments This model model is is is composed of over 450 individual protein domains ranging in in in in in in size from the the 60 protomers making up the the large spherical poliovirus (in (in green) to a a a a a single tiny insulin molecule (in (in magenta) The model was constructed using atomic level descriptions for for each molecule for for a a a a total of roughly 1 5 mil- lion atoms Detailed surfaces were computed for each type of protein using MSMS by Mi- chel Sanner which were then smoothed to a a lower resolution using the the the HARMONY spher- ical harmonic surfaces developed by Bruce Duncan Each type of protein was then copied and and placed either with symmetry or randomly using the the SymmetryServer developed by Tom Macke The image was rendered using the AVS dataflow visualization environment To pro- duce the the PHSCologram 64 different different views of the the scene were rendered simulating different different positions of the viewer’s eyes The three-dimensional effect is achieved by slicing and inter- leaving the the views vertically across the the image and using a a a a a a a a a plastic sheet with narrow vertical vertical lines to to channel a a a different view to to each eye Nanoscape I: Encounter in the Blood Stream 1998
Ellen Sandor & (art)n: Stephan Meyers Janine Fron and and and Fernando Orellana Arthur Olson and David Goodsell The Scripps Research Institute PHSCologram: Duratrans Kodalith Plexiglas
30 30 x 30 30 inches
Nanoscape I: Encounter in the Bloodstream