Page 14 - MDC Abstract Book & Guide

Michael Surette McMaster University
Michael Surette (PhD, University of Western Ontario 1991) and after postdoctoral training joined the University of Calgary in 1998 in the Department of Microbiology and Infectious Diseases. In 2010 he moved to McMaster University and is currently Professor and Canada Research Chair Interdisciplinary Microbiome Research in the Departments of Medicine, and Biochemistry and Biomedical Sciences, and director of the Farncombe Genomics Facility. He is a Fellow of the American Academy of Microbiology. Dr. Surette’s research combines culture-based approaches with next generation sequencing to address the human microbiome of the respiratory and gastrointestinal tracts in health and disease.
Presentation Title
Culture Enriched Metagenomics and the Human Microbiome
Abstract
The study of the human microbiome has largely been the focus of culture independent community profiling and metagenomics. It has often been cited that the diversity of the microbiome is really only accessible by culture independent methods., largely based on the assumption that the microbes are recalcitrant to routine culture approaches. By combining culture with next generation sequencing (culture enriched metagenomics), we show that greater microbial diversity and more complete genetic information is accessible than through culture independent approaches alone. Applications of this strategy to respiratory and gastrointestinal microbiomes will be presented.
Henrik Bjørn Nielsen Clinical-Microbiomics
Henrik Bjørn Nielsen, PhD, Chief Scientific Officer at Clinical-Microbiomics A/S, has since 2008 been a frontrunner in the field of microbiome research, which has led to a series of important scientific papers in the microbiome field, including his pioneering work on co-abundance binning of metagenomics data into metagenomic species, and in a 2016 Nature paper that report a three- pronged association study that links microbiome, serum metabolome and clinical data in pre- diabetic Danes. At Clinical-Microbiomics, Henrik Bjørn Nielsen leads the innovation and continued adaptation and development of new analysis concepts and methods in collaboration with clients and his team of expert bioinformaticians and biologist
Presentation Title
Ultra-high Resolution Microbiome Analysis