Page 33 - SONO 260 Chapter 13 The Male Pelvis
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PATHOLOGY OF THE SCROTUM MALIGNANT TESTICULAR TUMORS
AND TUMOR MARKERS
• THE MAJORITY OF MALIGNANT INTRATESTICULAR TUMORS ARE GERM CELL IN ORIGIN.
OTHER NON-GERM CELL MALIGNANT TUMORS INCLUDE SEX CORD-STROMAL TUMORS, LYMPHOMA, LEUKEMIA, AND METASTASES.
• THERE ARE TWO LABORATORY VALUES THAT ARE HELPFUL TO DIFFERENTIATE BETWEEN BENIGN AND MALIGNANT INTRATESTICULAR TUMORS, HCG AND AFP.
AN ELEVATION IN HUMAN CHORIONIC GONADOTROPIN (HCG) LEVELS IS FOUND IN CONJUNCTION WITH MALIGNANT INTRATESTICULAR TUMORS 60% OF THE TIME.
HCG IS PRODUCED BY THESE MASSES BECAUSE THEY CONTAIN SYNCYTIOTROPHOBLASTIC CELLS.
THESE CELLS, ALSO FOUND IN THE DEVELOPING PLACENTA, PRODUCE HCG IN THE MALE. Copyright © 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins
