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20 || AWSAR Awarded Popular Science Stories - 2019
drug resistance (i.e. their survival capacity in the presence of drugs). Hence, we found the mechanism how GMNCs influence the
(a) MDA-MB-468 (control)
cells in their environment, which was not well appreciated earlier.
(a) DOC-R-468-MNC (multinucleated cell)
 Fig. 1. (a) Control/Parental breast cancer cells; (b) multidrug resistant breast cancer cells with GMNCs (marked with a yellow arrow).
Conclusions
We had taken the matter of GMNCs very lightly and we should rectify this soon. In the past, some research groups observed that the GMNCs died after remaining dormant, and
hence these cells were not given adequate importance. Now we know, despite their dormancy, GMNCs (formed during drug resistance) can be very deceptive.
   

























































































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