Page 55 - Covid 2021 June 2021

The initiative has been developed with CAWACH support, a programme under the umbrella of NSTEDB of DST. The programme supports innovations in the areas of diagnostics, devices, informatics including bio-informatics and information management systems, any intervention for the control of COVID-19 and/or start-up ideas to address/mitigate various challenges faced by the country/society due to severe impact of COVID-19.
Contact Information:
Address: Turtle Shell Technologies, 587, First Floor, 9th A Main Rd, Indira Nagar 1st Stage,
Bengaluru, Karnataka 560038 Email ID: contact@dozee.io
Website: https://www.dozee.health/
Haystack Analytics provides genome-based COVID-19 solutions
Genomics has become increasingly mainstream in clinical sciences. Next-generation sequencing has ushered in the age of genomics providing the tools to gather all the relevant data for an in- depth inquiry and making simultaneous assessments possible. Today, genomics finds a footprint in identifying pathogens, antimicrobial resistance profiles, genetic disorders, oncology, and numerous non-communicable diseases. Genomics has the potential to translate into clinically actionable results that can help clinicians in making an early diagnosis. A start-up, Haystack Analytics, has developed genomic software solutions covering infectious genomics that take the turn-around time of genomics from weeks to days while preserving quality. This software is scalable to handle high sample throughput through an easy-to-use one-click format.
The start-up also supports and builds capabilities in genomic analysis–from the right design, to selecting the right sequencing strategy and the right bioinformatic to apply as per the requirements. Although the start-up has been working on genomics analysis for quite some time, 2020 has become synonymous with the pandemic which has further strengthened the need to make genomics analysis relevant and available for infectious disease. Solutions are needed at- scale genomic diagnostics for many diseases out there, one disease at a time.
In the COVID-19 pandemic, the start-up has made various genomics-based tools for contact tracing. They are sustainable and promote scalable identification of COVID-19 transmission, remote monitoring of transmission patterns, and also boost effectiveness of geospatial mapping of COVID-19 with genomic transmission mapping. The genomic analysis software specializes in infectious disease genomics bringing ease-of-use in analysing complex genomic data and transforming healthcare with automated one-click solutions. The services are driven by their experience in tuberculosis, infectious disease, epidemiology, molecular biology, and genomics. All the services are driven to pursue cutting- edge applications of genomics and support research and building genomic capabilities.
Some of the products developed are:
1. ΩTB - The ΩTB is a single test to give a complete genomic analysis of Mycobacterium tuberculosis. It identifies presence of resistance to 17 antibiotics, phylogeny, mixed infections, and hetero-resistance in 5 days.
2. ΩID - The ΩID is a single test to accurately identify >200 pathogens within 24 hours. The test covers bacteria, viruses and fungi that pose a significant threat to health.
3. ΩAMR - The ΩAMR is a single test to identify the presence of antimicrobial resistance within 24 hours. The test covers all key antibiotic classes.
4. ΩGut - The gut microbiome is diverse and varies among individuals. It has wide-reaching influences in our physiology ranging from metabolism, immune modulation and neurological functioning. ΩGut identifies dysbiosis whose identification can help in taking corrective and preventive action.
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