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C  CLINICAL RESEARCH




               In cylindrical refraction, the frequency percent  of  with the rule, oblique and against the rule axes of astigmatism be-
               fore operation were 21% ,44% and 35% ,respectively and  after operation  have been 18% ,24%  and 58% ,respectively.

               CONCLUSION
               Myoring operation provided significant improvement in BCVA, spherical and cylindrical refractive error .




               Subjective Outcomes in Symptomatic Patients wearing Dailies Total1 Multifocal Lens

               Jessica Mathews, OD; Beth Jackson, PhD; Jami Kern, PhD
               Alcon Research, Ltd., Fort Worth, TX, United States

               PURPOSE
               To report the subjective outcomes of DAILIES TOTAL1 Multifocal (DT1MF, delefilcon A, Alcon) contact lenses
               (CLs) in a population of symptomatic multifocal (MF) contact lens wearers.

               METHODS
               A total of 166 subjects were exposed to DT1MF CLs or their habitual MF CLs in this prospective, multi-site, ran-
               domized, bilateral cross-over clinical trial.  In order to qualify, subjects had to report eye dryness toward the end of
               the day and rate their habitual MF CLs as uncomfortable during the day.  Subjects completed the Contact Lens Dry
               Eye Questionnaire-8 (CLDEQ-8) at baseline based on their habitual MF CL and after 14±3 days of wearing DT1MF
               CLs, where lower scores indicate less symptoms.  Subjects rated comfort and dryness on a 10 point scale (1 =poor, 10
               =excellent) and also reported frequency of dryness symptoms.
               RESULTS
               The study population consisted of 77.1% female, with a mean age of 52.0±5.14 years.  The mean CLDEQ-8 score at
               baseline was 21.3±5.2 that significantly improved to 9.9±5.4 after two weeks of wearing DT1 MF CLs (p<0.0001).
               Subject-reported end of day comfort was 8.5±1.8, end of day dryness was 8.4±2.0, and dryness during digital device
               use was 8.4±2.2 with DT1MF CLs wear after two weeks. These mean scores after DT1MF CL wear were significant-
               ly better than habitual MF CLs (p<0.0001). Over 72% of subjects reported never or rarely having dryness symptoms
               after two weeks of DT1 MF lens wear.

               CONCLUSIONS
               Presbyopic patients who may have a compromised tear film may also experience difficulty wearing contact lenses.
               DT1MF CLs are a good option for patients who report discomfort and dryness with their current CLs.

               CONFLICT OF INTEREST DISCLOSURE
               The authors are employees of Alcon Research, Ltd.


               Alcon Multifocal Contact Lenses for Presbyopia Correction


               Jessie Lemp , Beth Jackson , Jami Kern 1
                          1
                                        1
               1 Alcon Research, Ltd. Fort Worth, TX, United States
               PURPOSE
               To describe visual outcomes in patients fitted with three Alcon multifocal (MF) contact lenses (lotrafilcon B, nelfil-
               con A, delefilcon A) that contain the same Precision Profile optical design.

               METHODS
               In the first study, 27 subjects were fit with lotrafilcon B and nelfilcon A MF lenses in a prospective, single-site, bilateral
               cross-over trial. In the second study, 166 subjects were fit with delefilcon A MF lenses in a prospective, multi-site, bi-
               lateral trial.  LogMAR visual acuity (VA) at 40 cm (near), 80 cm (intermediate), and 4 m (distance) was collected after
               the 1-2 week follow-up period.  At dispense, subjects were asked to rate their vision quality at near, intermediate and
               distance on a 10-point scale (1=poor and 10=excellent) and at follow up they were asked to rate their overall vision.




      34                         CANADIAN JOURNAL of OPTOMETRY    |    REVUE CANADIENNE D’OPTOMÉTRIE    VOL. 79  NO. 2
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