Page 28 - Org 3 theoritical book 2024-25

Clinical Pharmacy PharmD - 2024/2025 Level 2 Pharmaceutical Organic Chemistry-3 (PC 305)
Prefix of attached component to the parent ring

Pyrazole ---------> pyrazolo Indole ----------> indolo Pyran --------> pyrano
Exception:

Furan --------------> furo thiophene ----------> thieno

Imidazole ---------> imidazo quinazoline ---------> quino

Pyridine -----------> pyrido isoquinoline --------> isoquino

Pyrimidine --------> pyrimido naphthalene ---------> naphtho

Benzene -----------> benzo benzofuran ----------> benzofuro

Rule 5:

1) If a heteroatom is common to both rings, it must be considered as a member of

both rings.

2) By numbering of such compounds, the common heteroatom takes its own

number, in contrast to carbon atoms in the fusion position, which are not

numbered