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Name of disease: Malaria

Cause and      Malaria is caused by a unicellular parasite called Plasmodium, transmitted to humans
transmission   through the bite of an infected female Anopheles mosquito. The mosquito becomes
               infected when it draws the blood of an infected human. The parasite develops in
               the mosquito’s body and after eight days it can transmit the disease. In Jerusalem
               the mosquito that transmits the disease has been of the species Anopheles claviger.
               This species is found in Europe, and our country is the southernmost extent of
               its distribution. Anopheles claviger, which adapted itself to the cool conditions of
               Jerusalem’s cisterns, was responsible for the extensive presence of the disease in the
               city until the period of the British Mandate.

Symptoms       Malaria causes high fever, headaches, sweating and chills, and lasts from one to three
and            days. Left untreated, the disease can be fatal, especially among children.
progression

Treatment      The rst e ective medication for malaria was quinine, developed at the beginning
and            of the 18th century and produced from the bark of a South American tree. Since that
medications    time many drugs have been developed, to most of which the parasite has developed
               immunity (the way bacteria become immune to antibiotics). The most e ective drug
               against the disease today is Artemisinin.

Notes          Malaria is found today mainly in sub-equatorial Africa and in South America. A
               few hundred million people contract the disease every year; about half a million
               die from it. Malaria was the most common and signi cant ailment in this region
               until the British conquest of the area in World War I. In the 1920s the Mandatory
               health authorities took action to eradicate the disease, in cooperation with Jewish
               community institutions and according to a plan devised by Prof. Israel Kligler. Only in
               1967, after decades of ghting the disease, did the World Health Organization declare
               Israel malaria-free.

Name of        Dr. Zalman Greenberg,  Signature
physician      bacteriologist

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