Page 61 - IPCoSME 2021

1 INTERNATIONAL POSTGRADUATE CONFERENCE ON SCIENCE AND MARINE ENVIRONMENT 2021
st
(IPCoSME 2021)
“Environmental Sustainability Enhancement Through the Collaboration of Sciences”

RC-06

VIBRIOSIS CONTROL STUDY OF BIOSYNTHESISED GOLD NANOPARTICLES
(AuNPs) IN WHITELEG SHRIMP, Litopenaeus vannamei

1
MOHAMAD SOFI ABU HASSAN , NOOR ANIZA HARUN 1,2*

1 Higher Institution Centre of Excellence (HiCOE), Institute of Tropical Aquaculture and
Fisheries (AKUATROP), Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu

2 Advanced Nano Materials (ANoMA) Research Group, Faculty of Science and Environment,
Universiti Malaysia Terengganu

*Corresponding author email: nooraniza@umt.edu.my

Abstract: Acute Hepatopancreatic Necrosis Disease (AHPND) is a newly emerged bacterial

pandemics caused by a strain of bacteria named Vibrio parahaemolyticus, severely affected

Whiteleg Shrimp, Litopenaeus vannamei. AHPND has caused a significant 70 % decline in
shrimp aquaculture and a collective loss exceeding US $43 billion across Asia. Possible control

measures to reduce the risk of AHPND outbreaks have to be found out urgently. Gold
nanoparticles (AuNPs) have been known to have antimicrobial properties arise from their size

and materials. Given its size advantage that is small enough and comparable with the dimension

of bacteria. This gives it the ability to attach to the biological entity without changing its
functions and induced its toxicological effect on the bacteria. However, there are several safety

concerns on environmental toxicities associated with the use of nanoparticles (NPs) especially
their behaviour and fate in aquatic organisms and the environment. Therefore, this study will

investigate the utilisation of green-technology produced gold nanoparticles (AuNPs)

synthesised through a marine worm, Marphysa moribidii. This study aimed to evaluate the
morpho-physicochemical, antimicrobial properties and toxicity of green synthesised AuNPs

administered orally in shrimp against an experimental infection with V. parahaemolyticus. In
the meantime, the survival rate and tissue damage through histology of challenged shrimps will

be investigated and hope the green synthesised AuNPs will produce a promising alternative to
the control of V.parahaemolyticus in the shrimp industry, by extension contribute to the

development of strategies to control AHNDP disease.

Keywords: Acute Hepatopancreatic Necrosis Disease (AHPND), Litopenaeus vannamei,
Vibrio parahaemolyticus, aquaculture, gold nanoparticles

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