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ONCOLOGY UPDATE in South Florida ...ONCOLOGY UPDATE in South
              A Special Thank

                  You to the                    Reducing Toxicity from Prostate Cancer Radiotherapy

              December 2018                    While radiotherapy has proven to be a                                  related to the gel and it remains stable
                                             very effective treatment for men with                                    throughout radiation therapy before
            Host of the South                prostate cancer, the high doses of radia-                                being absorbed by the body.
                                             tion required to kill cancer cells in this
            Florida Healthcare               area have traditionally come with the                                    Reducing Toxicity
                                                                                                                        In a randomized, prospective clinical
                                             risk of toxicity to organs that surround
                                             the prostate. The rectum, which sits                                     trial, it was demonstrated that the hydro-
           Networking Group                  directly behind the prostate, is of partic-                              gel is well tolerated by patients, easy to
                                             ular concern, with high energy X-rays                                    place, and, most importantly, significantly
                                             potentially causing injury to the rectal                                 reduces the volume of rectum that receives
                                             wall, diarrhea, or bleeding.                                             high dose radiotherapy. This has directly
                                               To reduce the dose of radiation                                        translated to a reduction in rectal toxicity
                                             received by the rectum during treatment,                                 and its side effects among patients who
                                             radiation oncologists currently utilize                                  received the product.
                                             intensity  modulated   radiotherapy      BY AARON FALCHOOK, MD             Another benefit to this approach is that
               DELRAY BEACH                  (IMRT), a technique where the radiation                                  it can be used with many different types of
             MEDICAL CENTER                  beam is delivered from multiple direc-  to physically separate the two organs is   radiation, including:
                                                                                                                        • Fractionated radiotherapy - small to
                                             tions with varying intensity, reducing the
                                             amount of rectum directly in the path of   one approach being tested. Another   moderate doses of radiation given daily for
                                             radiation. We also use image guided   product that may help reduce radiation   four to eight weeks
              For information about          radiotherapy (IGRT) to precisely verify   from reaching the rectum are implanted   • Stereotactic radiosurgery - high doses
               our next meeting of           the location of the prostate and rectum   calypso fiducial markers, which emit a   of radiotherapy delivered in four to five
                                             to ensure the target is aligned correctly   radiofrequency signal that helps localize   treatments over one to two weeks
                     SFHNG,                  within the treatment machine. Still, nei-  the prostate. In essence, it’s similar to a   •  Brachytherapy - radioactive seed

                    please email             ther of these approaches changes the fact   GPS that tracks the prostate’s motion   implants
                                             that the rectal wall is in direct contact   during radiotherapy treatment to ensure   Many doctors in the U.S. and overseas
                     charles@                with the prostate, making it unavoidable   accurate delivery of radiation.    are now utilizing at least some of these
             southfloridahospitalnews.com    that at least a small portion of the rectum   One of the spacer products that has   approaches to benefit patients by minimiz-
                                             will receive the full dose of radiation.   received FDA approval is a polyethylene   ing rectal toxicity during the treatment of
                                                                                  glycol hydrogel that fills the plane   prostate cancer.
                                             Looking for Solutions                between the prostate and rectum. The
                                               To address the issue of the rectum’s   gel is injected as a liquid and solidifies   Dr. Aaron Falchook is a board-certified
                                             close proximity to the prostate during   where it’s placed, creating a barrier that   radiation oncologist at the Memorial
                                             treatment, several approaches can be   prevents the rectum from receiving the   Healthcare System’s Memorial Cancer
                                             considered to address the problem,   high dose radiation required to kill can-      Institute. Connect with them at
                                             although some are still in the experimen-  cer cells in the prostate. Patients don’t        (954) 265-4325 and
              THE REGION’S MONTHLY NEWSPAPER FOR HEALTHCARE PROFESSIONALS & PHYSICIANS
                                             tal phase. The use of hyaluronic acid gel   experience any symptoms or discomfort     www.mhs.net/services/cancer.














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         18                        January 2019                                                           southfloridahospitalnews.com                                                                       South Florida Hospital News
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