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University of Miami and Other Florida Institutions Are Awarded a $15

                             Million National Alzheimer’s Disease Research Center




          A consortium of Florida institutions   associate director of 1Florida ADRC and
        including the University of Miami Miller   director of the Center for Cognitive
        School of Medicine has been awarded a   Neuroscience and Aging at the
        $15 million grant to collaborate on   University of Miami Miller School of
        Alzheimer’s disease research.        Medicine.
          The five-year National Institutes of   “The Miller School is recruiting hun-
        Health/National Institute on Aging grant   dreds of older adults from our local com-
        brings together top Florida researchers to   munity,” said Dr. Loewenstein. Their
        focus on better understanding how to   focus is on engaging African American
        diagnose, treat, prevent, and potentially   and Hispanic older adults to make sure
        cure Alzheimer’s in diverse populations.    they are well represented, because these
          The 1Florida Alzheimer’s Disease   groups are historically largely under-rep-
        Research Center, or 1Florida ADRC, will   resented in aging research, including
        be recruiting participants from the   studies looking at Alzheimer’s disease.
        University of Miami Miller School of   “I am the daughter of Cuban exiles; the
        Medicine, the University of Florida, and   first to be born in this country. Spanish
        Mount Sinai Medical Center in Miami   was my first language. Miami has nur-
        Beach. Investigators from these institu-  tured this multicultural identity and I am
        tions will also be collaborating with   privileged to bring it to the forefront of
        Florida Atlantic University and Florida   my work,” said Rosie E. Curiel Cid,
        International University.            Psy.D., leader of the1Florida ADRC
          “We are honored that this Alzheimer’s   Outreach,  Recruitment   and
        Disease Research Center is one of 31 cen-  Engagement Core, associate professor   (l-r) University of Miami researchers Dr. Rosie Curiel, Dr. David Loewenstein,
        ters of excellence designated by the   and chief, cross-cultural neuropsychol-                    and Dr. Elizabeth Crocco
        National Institute on Aging. Of the 31   ogy and cognitive neuroscience, in the   the methods we develop to detect and   1Florida ADRC study. LASSI-L is a scien-
        centers in the U.S., the 1Florida ADRC is   Center for Cognitive Neuroscience and   treat diseases of the aging brain are gen-  tifically proven measure that is highly
        the only funded center in Florida,” said   Aging (CNSA). “One of the greatest chal-  eralizable to all older adults. The CNSA   sensitive to early Alzheimer’s disease
        David Loewenstein, Ph.D., ABPP/CN,   lenges in aging research is ensuring that
                                                                                  is committed to addressing this by devel-  brain pathology and can pick up early
                                                                                  oping tools and methods that are cross-  changes in memory before traditional
                                                                                  culturally applicable.”             cognitive testing detects the disease.
                                                                                   To better understand diseases of the   Elizabeth Crocco, M.D., chief of geri-
                                                                                  aging brain, even decades before they   atric psychiatry and director of UM’s
                                                                                  occur, the ADRC scientists have an   state-funded Memory Disorders Clinic
                                                                                  expertise in studying people who don’t   and medical director of the CNSA, will
                                                                                  yet have symptoms but might be con-  be running the medical aspects of the
                                                                                  cerned about their risk for developing   1Florida ADRC, and Tatjana Rundek,
                                                                                  Alzheimer’s for another reason, such as   M.D., Ph.D., professor of neurology and
                                                                                  family history. They also study older   Evelyn F. McKnight Endowed Chair for
                                                                                  adults who may have thinking or memo-  Learning and Memory in Aging, is co-
                                                                                  ry problems but haven’t yet been diag-  leading the ADRC’s educational core
                                                                                  nosed, as well as people who have been   with Glenn Smith, Ph.D., ABPP/CN,
                                                                                  diagnosed with early mild cognitive   from the University of Florida. The
                                                                                  impairment.                         1Florida ADRC will help train the next
                                                                                   “People in the study will receive annu-  generation of scientists in Alzheimer’s
                                                                                  al evaluations including comprehensive   and other neurodegenerative diseases.
             This is a M          inor      Inconv                                neuropsychological testing, a careful   Florida is home to about 12% of the
                                                        v venience.
                                                                                  clinical examination, an MRI scan of the   approximately 5.4 million people in the
                                                                                  brain and an amyloid scan,” Dr.     U.S. who have Alzheimer’s disease.
                                                                                  Loewenstein said.
                                                                                   Dr. Loewenstein and colleagues devel-    For more information about 1Florida
                                                                                  oped a novel cognitive stress test, called   ADRC, including how to participate, visit
                                                                                  the Loewenstein-Acevedo Scales for               www.1floridaadrc.org, email
                                                                                  Semantic Interference and Learning               info@1floridaadrc.org or call
                                                                                  (LASSI-L) test, which will be used in the   (352) 273-7425 or (305) 355-9080.





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         22                       September 2020                                                       southfloridahospitalnews.com                                                                       South Florida Hospital News
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