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• They consist of delicate connective capsule surrounding highly coiled non-
myelinated terminal branches that form a ball-like mass (glomerulus).
• They are sensitive to touch and pressure sensation.
Golgi tendon organs (Neurotendineous spindles)
• They are found at muscle-tendon junctions and are sensitive to tension of
muscles.
• They consist of thin connective tissue capsule surrounding unmyelinated
axon that forms spray-like branches ending in small dilatations.
Ruffini corpuscles
• They are found in dermis, fascia, ligaments and joint capsule.
• They are similar to neurotendinious junction and are sensitive to mechanical
distortion of the limbs.
Neuromuscular spindle (muscle spindle)
• They are large (up to 6 mm long and less than 1 mm in diameter),
encapsulated, lymph-filled, fusiform structures found within skeletal
muscles. Each spindle contains from 2-10 modified skeletal muscle fibers
called intrafusal fibers, in contrast to extrafusal fibers located outside the
spindle.
• Two types of intrafusal fibers are recognized: Nuclear bag fibers: have
dilated non-striated middle zone filled with nuclei. Nuclear chain fibers:
are smaller than nuclear bag fibers and their nuclei are arranged in a single
row.
Two types of sensory receptors are associated with the intrafusal fibers:
1. Annulo-spiral endings: where the non-myelinated endings of large myelinated
sensory fibers are wrapped around the nuclear region of the intrafusal muscle
fibers.
2. Flower-spray endings: of smaller myelinated sensory fibers and are located on
the striated portion of the intrafusal fibers.
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