Page 16 - Randlab Global Brochure Australian Edition

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RESPIRATORY PRODUCTS
Airway TmpsTM
Oral bronchodilator and antibacterial for the treatment of respiratory diseases
APVMA Approval No. 61474/500/0807 (Australia) | ACVM No. A10158 (New Zealand)
Randlab supports responsible Antimicrobial Stewardship.
When antibiotic cover and bronchodilation is required.
ACTIVE CONSTITUENT
Clenbuterol Hydrochloride 21.44 μg/g Sulfadiazine 335 mg/g
Trimethoprim 67 mg/g
PACK SIZE 500g jar
INDICATIONS
For the treatment of respiratory disease in horses caused by organisms susceptible to an antibiotic trimethoprim/sulfadiazine combination. Treatment of respiratory conditions characterised by restriction of the airways, including bronchospasm and obstruction resulting from bacterial and viral infection, bronchitis and bronchopneumonia.
PHARMACOLOGY
Airway Tmps Oral Powder is formulated for the treatment of respiratory disease in horses caused by organisms susceptible to the trimethoprim/sulfadiazine antibiotic combination. These include; Staphylococci, Streptococci, Fusobacterium, Eneterobacter, Corynebacterium (excluding Rhodococcus equi), Salmonella, Shigella, Klebsiella, Pasteurella, Haemophilus, Proteus spp and most E.coli, some Brucella and Nocardia spp. Most Pseudomonas spp are insensitive.
Clenbuterol is a bronchodilator with minimal effect on the cardiovascular system. Clenbuterol also has a stabilising effect on mast cells, preventing the release of histamine, serotonin and bradykinin and therefore has a beneficial effect to clear mucociliary discharge.
CONTRAINDICATIONS
Airway Tmps Oral Powder will potentiate the action of corticosteroids and antagonise the effects of prostaglandin F2 and oxytocin. Beta adrenergic agents adversely affect the action of Airway Tmps. Concurrent treatment of horses with these medications is not recommended. Airway Tmps Oral Powder should not be used in horses during the last 14 days of gestation, as uterine contractions may be prevented.
“Playing polo is like trying to play golf during an earthquake”. Sylvester Stallone (American actor,
producer, director and screenwriter).
ORAL ADMINISTRATION IN HORSES
DOSE: 30mg/kg twice daily in feed. (30mg/kg = 25mg Sulfadiazine + 5mg trimethoprim). One level scoop (9g) orally per 250kg bodyweight to be added to feed twice daily for 6 to 10 days. Twice daily dosing is recommended to maintain therapeutic levels.
Administer on damp food with honey or molasses to avoid sifting of powder. Alternatively, Airways Tmps may be made up as a paste with molasses, honey or Karo Syrup and administered over the back of the tongue.
Whenever possible, bacterial culture and sensitivity testing should be carried out prior to initiating treatment with Airway Tmps as well as in cases with non-responsive or chronic infections.
HORSE HACK: Airways Tmps can be easily administered as a “powder sandwich” over the back of the tongue. Cut the top off a 60mL syringe at the 2mL mark with a bread knife or hacksaw. Withdraw the plunger to 60mL. Put two teaspoons of molasses or honey in the syringe, followed by the prescribed dose of Airways Tmps and a further two teaspoons of molasses or honey. Administer to the horse over the back of the tongue. As well as adding some flavouring, the molasses or honey stops the horse spitting out the dose.
Racing/Event Withholding Period: If used in performance animals, the regulations of the relevant authorities regarding medication should be observed.
Storage: Store below 30°C (Room temperature). Protect from light.
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