Page 7 - OrthoFeed-Jun'21

Orthopedic
Osteomorphs – the surgical robots

power ranger bone cells

Orthopedic procedures using robots are less
Institute of Medical Research have intrusive and deliver reproducible accuracy,
discovered a new type of bone cell resulting in shorter hospital stays and quicker
called ‘osteomorphs’ that may recovery times.
reveal new therapeutic approaches
for osteoporosis and other skeletal i. Semi-active robots-
diseases. Osteoclasts split into By offering an eminent combination of
smaller fragments to form flexibility and accuracy, these robots are
osteomorphs which fuse together outperforming the conventional orthopedic
forming osteoclasts again. surgical robots and proving their mettle in
Therefore, the cosmos has called it delivering effective care. Semi-active robots
a “recyclable cell”. also provide user-friendly interfaces for easy
Figure - 3D microscopy image of
access and make the surgeries minimally
osteomorphs
They are also found in the blood invasive as well as highly accurate.
(source-cosmosmagazine.com)
and bone marrow wherein they are Smart sensors will have
maintained as reserve of cells that ii. Patient-specific templates
A better understanding of these
Frodosome - are ready to fuse and deploy when cells and the genes that control These templates enable the development of applications in four arenas-
osteoclasts are needed again.
3-dimensional surgical plans for
them may reveal new therapeutic
new organelle Researchers found that 17 out of a targets for skeletal disease. implementation, along with rapid designing i. Smart Tools in the OR: Smart instruments with embed-
total of 40 genes detected in
named after osteomorphs impact the amount of rug-targets-for-osteoporosis-and-other-s and manufacturing of tailor-made drilling and ded sensors will help surgeons position the implant and balance
cutting templates. Robotic intervention in
'the hobbit' hero bone and bone strength, indicating keletal-diseases/ orthopedic surgeries offers immense scope for the load during surgery.
a critical role in bone maintenance.
the effective application of these templates
2.https://cosmosmagazine.com/science/ ii. Smart Diagnostics on Demand: It will relay diagnos-
During animal experiments have biology/new-recyclable-bone-cell/ onto the affected joint surfaces.
Scientists have recently discovered a been linked to human gene tic data from inside the patient to the surgeon during regular
new membrane-less fluid-like variants that lead to skeletal 3.https://www.eurekalert.org/pub_releas patient follow-up visits.
structure involved in bone metastasis. dysplasia and control bone mineral es/2021-02/giom-nto021821.php#:~:text= Smart sensors for better
It is unofficially named as the The%20new%20cells%2C%20which%20t diagnosis and iii. Smart Diagnostics by Exception: It will send
he,yet%20unexplored%20targets%20for
"frodosome" or "wise" organelle. density. %20therapy. wireless data when they detect issues, like early infection,
Source - patient-care osteolysis and stress shielding.
It was discovered accidently while 1.https://www.genengnews.com/news/new-
scientist were studying DACT1 gene bone-cell-type-identified-could-point-to-d Smart implants provide built-in sensors to
which suppresses critical signaling offer real-time tracking and post-operative iv. Treatment by Exception: It will detect a problem and
pathways in cells that help in early evaluation details to surgeons for better “self-treat” the patient by delivering drug therapies or stimula-
bone development and influence tion locally as needed. They may deliver antibiotics or growth
cancer progression. The researchers patient safety across the clinical process. factors long after surgery.
think that frodosomes form when the
protein DACT1 binds to other Source -
free-floating proteins and molecules
in the cell. 1.https://www.news-medical.net/news/20210309/Princeton-researche
rs-discover-previously-unknown-organelle-that-plays-role-in-bone-m
The DCT1 gene regulates the Wnt etastasis.aspx
signaling pathway of cancer Source -
metastasis. The frodosome plays a 2.https://www.livescience.com/new-frodosome-organelle-cancer.html 1.https://www.persistencemarketresearch.com/market-research/orthopedic-s
part in the spread of bone tumor by urgical-robots-market.asp
suppressing the Wnt pathway. 3.https://www.princeton.edu/news/2021/03/09/princeton-team-disco 2.https://orthostreams.com/2020/09/update-on-the-12-major-surgical-roboti
cs-systems-today/
It's too early to say whether the vers-new-organelle-involved-cancer-metastasis#:~:text=Princeton%20 3.https://orthostreams.com/disruptive-trend-in-orthopedics-the-smart-impla
frodosome will be a good drug cancer%20researchers%20Yibin%20Kang,materials%20merge%20into nt-revolution/
target in metastatic cancer, but the %20each%20other. 4.https://www.imcgrupo.com/the-latest-technological-innovations-in-orthop
discovery is definitely an exciting edic-surgery-2020-technology/
phenomenon. Disclaimer: The contents of this page are formulated solely to render information about
Smart the latest technologies and inventions in orthopedics. This information is sourced from
sensors various online resources and may contain repetition of words, thoughts and ideas