Page 30 - Ebook Imunologi_Neat2
P. 30
Overview of Complement
Classical Pathway Lectin Pathway Alternative Pathway
Antibody binds to specific Mannose-binding protein Pathogen surface creates
antigen on pathogen surface binds pathogen surface environment conducive to
complement activation
Clearance of Complement Activation
Apoptotic Cells
Formation of C3 and C5 convertases
Inflammatory response
Membrane Attack Pathway
Cytolysis of some pathogens
Opsonization & phagocytosis Clearance of
of some pathogens Immune complexes
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