Page 183 - Biochemistry2 (08PB403)
P. 183

• After carbohydrate meal Glucose is transported to portal blood to
    the liver.

• About 40% of glucose passes to the blood circulation stimulating
    insulin secretion and taken up by brain, muscles, adipose tissue and
    liver. The remaining 60% of glucose is taken up by the liver and
    converted by Glucose-6-phosphate by glucokinase.

• G-6-P will has one of the following fates in the liver:

     – Conversion to glycogen (Glycogenesis) stimulated by insulin.

     – Conversion to fatty acids (Lipogenesis) stimulated also by
        insulin.

3- Renal Regulation

• Circulating blood glucose is filtered in glomerular filterate and
   reabsorbed again by certain tubular enzymes. This saves blood

glucose from loss in urine.  187
   178   179   180   181   182   183   184   185   186   187   188