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Secondary Metabolites

I. Alkaloids

Definition:

i- Alkaloids (alkali-like) are naturally occurring compounds.

ii- They are basic compounds.

iii- They contain one or more nitrogen atoms usually in a heterocyclic ring.

iv- They usually have a marked physiological action on man or other
animals.

v- The name proto-alkaloid or amino- alkaloids is sometimes applied to

compounds such as ephedrine and colchicine which have their nitrogen in

a side chain.                                     OMe
                                      MeO

OH CH3                                MeO
          NHCH3
                                                               NHCOCH3

Ephedrine                             MeO
                                                  O

                                           Colchicine

       By agreement, chemical rules designate that names of alkaloids
should end with the suffix (ine).

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