Page 191 - Applied Pharmacognosy

Types of Chemical markers

4.Complexity of quality control
process:

Analytical analytical methods covering:
assay *primary amino acid sequence changes
(e.g. deamination, oxidation)
*post-translational modifications (e.g.,
glycosylation)
*higher order structural changes (e.g.,
secondary folding, aggregation).

functional activity assays (i.e., in required that can
discern which vivo, in vitro) (Bioassay) are Bioassay