Page 97 - Clinical Biochemistry

Case-1:
A male age 50 presented with pyrexia. He was clinically dehydrated and oliguric.
Laboratory Data:
•Creatinine 4.4 mg/dl (N: 0.5-1.5)
•BUN 100 mg/dl (N: 8 -20)
•Bicarbonate 16 mmol/l (N: 23 to 30 mEq/L)
•Sodium 140 mmol/l (N: 136-146)
•Potassium 6.9 mmol/l (N: 3.5-5.3)
•Seum osmolality 305 mmol/kg
•Urine osmolality 629 mmol/Kg
What does these biochemistry results indicate about the patient's condition?
Case-2:
A 40-year-old women with chronic kidney failure who is being treated by dialysis. Her serum
biochemistry just prior dialysis showed:
Laboratory Data:
•Creatinine 4.4 mg/dl (N: 0.5-1.5)
•BUN 120 mg/dl (N: 8 -20)
•Bicarbonate 11 mmol/l (N: 23 to 30 mEq/L)
•Sodium 129 mmol/l (N: 136-146)
•Potassium 5.9 mmol/l (N: 3.5-5.3)
•Choloride 100 mmol/l (N: 98-108)
What is the significance of these results? What other biochemical tests should be performed?

Objectives:

By the end of this chapter, the student should identify the structure of kidney, endocrine
Function of Kidney, kidney diseases and renal function tests.