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4- Hormonal agents – Female patients
Combination oral contraceptives Once daily
(estrogen/progestin)
Spironolactone 50 to 100 mg/day in 1
(oral antiandrogen) divided doses§
5- Oral retinoid 0.5 mg/kg/day, increas
mg/kg/day in 1 or 2 eq
Oral isotretinoin doses; total dose 120 t
over 20 weeks
