Page 439 - COMMUNITY PHARMACY PRACTICE

What’s NEW?- IMPORTA

Before 2020- we could only use androgen modulati
patients in the form of oral contraceptives and spi

Clascoterone 1% cream inhibits sebum production
androgen receptors in sebaceous gland cells.
The topical treatment, now available in the United
approved for patients over 12 years, provides an a
treatments such as isotretinoin.

"Sebocyte suppression is a key step in the cascad
increased [Cutibacterium] acnes bacterial activity
pathways that contribute to inflammation,” Haleh B
FAAD, founder of Dr B Dermatology in Beverly Hills, California,

This is an antiandrogen in the skin, but it is quickly
skin and does not act as an antiandrogen systemi
to be worried about systemic antiandrogen effects