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cer disease – PPIs are first-line antisecretory
n the treatment of peptic ulcer disease.
ophageal reflux disease – PPIs are indicated in
with gastroesophageal reflux disease, including for
ment of erosive esophagitis and as maintenance
n patients with severe erosive esophagitis or
esophagus.
Ellison syndrome – PPIs, often in high doses, are
to control gastric acid hypersecretion in patients
rin-secreting tumors.
sociated ulcers – PPIs are indicated in the primary
on of gastroduodenal ulcers associated with NSAID
on of Helicobacter pylori – PPIs are a component of
rst-line and salvage therapy regimens for H.
ection.
