Page 67 - COMMUNITY PHARMACY PRACTICE
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02/04/2024
At-risk patients
Extreme of age: Gender Concurrent drug Concurrent
(elderly patients- (pregnancy) usage disease, e.G.
Respiratory
neonates and
infants) disease
pharmacokinetic variables, e.G. Genetics, e.g. Patients with a
Renal or Hepatic function, thyroid Glucose-6- history of
phosphate
dysfunction ADRS/allergies.
• pharmaceutical factors, e.G. dehydroge- nase
(G6PD) deficiency. 138
Nature of dosage Form or
excipients
138
139
Fringe benefits of adverse drug reactions
Drug ADR benefit
Codeine constipation Off label use in
Erythromycin diarrhea
nifedipine diarrhea Off label in hospitals
to stimulate motility
sildenafil Postural For Reynaud s
hypotension disease
(vasodilator)
CVS Erectile dysfunction
139
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