Page 4 - Clinical biochemistry

Biosynthesis of heme................................................................................................................................. 25
Inhibitors of heme synthesis ..................................................................................................................... 27
Hemoglobin Derivatives ............................................................................................................................ 27
Types of Hemoglobin................................................................................................................................. 30
Chapter 3 ........................................................................................................................................................... 33
ENZYMES ....................................................................................................................................................... 33
☻Definitions: ............................................................................................................................................ 34
☻Discovery of Enzymes ............................................................................................................................ 34
☻Nomenclature........................................................................................................................................ 35
Factors affecting enzyme activity .............................................................................................................. 48
Enzymes in Clinical Biochemistry.................................................................................................................. 59
Chapter 4 ........................................................................................................................................................... 66
BIOENERGETICS ............................................................................................................................................. 66
Bioenergetic processes biological oxidation ............................................................................................. 66
The chemistry of metabolism........................................................................................................................ 72
1. Oxidation-reduction reactions............................................................................................................... 72
Chapter 5: .......................................................................................................................................................... 95
Nucleotides Synthesis and Degradation........................................................................................................ 95
PURINE RIBONUCLEOTIDES SYNTHESIS:.................................................................................................... 95
PURINE CATABOLISM ................................................................................................................................ 98
SALVAGE PATHWAY OF PURINES: ........................................................................................................... 100
PYRIMIDINE RIBONUCLEOTIDE SYNTHESIS ............................................................................................. 102
DEGRADATION OF PYRIMIDINES: ............................................................................................................ 103
Chapter 6 ......................................................................................................................................................... 104
1) LIPID CHEMISTRY .................................................................................................................................. 104
Examples of Lipid:.................................................................................................................................... 104

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