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2- Small quantity of V.O. (Cannibene).
3- Natural bases as choline, trigonelline, flavonoids, cannabisativine alkaloid, and others.
Cannabis produces the best hemp (for fiber production) when grown in a temperate climate,
whilst the more active samples of Indian hemp are usually associated with warmer climates. Plant
growth and development, and often the nature and quantity of secondary metabolites, are
affected by temperature, rainfall, aspect, length of day (including the quality of light) and altitude.
Such effects have been studied by growing the plant in different climatic areas and observing
variations (the seeds of cannabis, grown in England wer rich in CBD and devoid of THC, while
seeds cultivated in Sudan started to produce THC in the first generation and in the second
generation contained up to 3.3% THC with a further decrease (down to 0% in some plants) of
CBD).

Cannabis evaluation:

The general view that cannabis preparations can be evaluated on their Δ9-THC content neglects
other active components, and in attempts to classify cannabis on the basis of its narcotic/fiber
content a number of systems, some very complex, have been devised. A relatively simple
relationship introduced by Waller is based on the combined Δ9-THC and cannabinol (CBN) in
relation to cannabidiol (CBD).
The phenotype is expressed as:

A sample with a value greater than 1 = a drug type of cannabis; a sample with a value less than 1
= a fiber type.

Actions and Uses:

Δ9-THC is the principal psychoactive constituent.
Δ8-THC is almost as active but is only present in the plant in small amounts.
Cannabinol is less potent.
Cannabidiol, lacks the psychotropic properties (presents a modulating effect on Δ9-THC
psychoactive activity) and has anticonvulsant and possible analgesic and anti-inflammatory
effects.

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