Page 43 - phytochemistry I - PharmD Clinical

(3) Carminative effect:
Anise fruits oil, basil, fennel, chamomile, coriander, caraway fruits, and
peppermint oil.

(4) Spasmolytic effect:
It is observed as relief of spasms of smooth muscles of intestines and
gall bladder. ex. Chamomile, caraway, fennel, orange and peppermint oil
as well as cinnamon oil.

5) Circulation stimulating effects:
Some V.O. has stimulating effect on the respiration and circulation
centers. Ex: Camphor, rosemary, lavender and peppermint oils.

Undesirable side effects of V.O:
1- Allergic effect:
V.O. have no allergic effect but upon storage, terpene hydrocarbons
(contain double bonds) (have no allergic effect) will be converted into
terpene hydroperoxides (have allergic effect).

2- Phototoxic and photosensitizing effect:
Some V.O. containing furanocoumarins (are used in the treatment of
vitiligo) can after an initial photosensitizing effect.
They give phototoxic reactions which can be observed as erythema
(Redness of the skin, caused by hyperemia, increase of blood flow) and
formation of blisters.

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