Page 124 - BIOCHEMISTRY II
P. 124

HMP SHUNT [Hexose Monophosphate Pathway] /
                PPP [Pentose Phosphate Pathway]

• Principle pathway for oxidation of Glucose-Glycolysis & TCA
• HMP is an alternative pathway for oxidation of Glucose-not for

    Energy
• Occours in cytosol in all cells.
• Provides: NADPH [reductive synthesis] & Pentoses [for NA

    synth].
• Most common at the site of synthesis:

    Liver [phospholipid, FA synth, Cholesterol], adipose tissue [FA
    synth], lactating mammary gland [FA synth], adrenal cortex
    [Cholesterol, steroid hormone synth], testes & other endocrine
    glands concerned with steroid synthesis and RBC.

                                                                                                                                   123
   119   120   121   122   123   124   125   126   127   128   129